Alzheimer disease (AD) is the most common neurodegenerative disorder worldwide and is
at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD …

Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …

Calcium is involved in many facets of neuronal physiology, including activity, growth and
differentiation, synaptic plasticity, and learning and memory, as well as pathophysiology …

Alzheimer disease (AD) is the most common form of adult dementia. Its pathological
hallmarks are synaptic degeneration, deposition of amyloid plaques and neurofibrillary …

Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …

Calcium modulates many neural processes, including synaptic plasticity and apoptosis.
Dysregulation of intracellular calcium signalling has been implicated in the pathogenesis of …

Perturbed neuronal Ca 2+ homeostasis is implicated in age-related cognitive impairment
and Alzheimer's disease (AD). With advancing age, neurons encounter increased oxidative …

Alzheimer's disease (AD) is the disease of lost memories. Synaptic loss is a major reason for
memory defects in AD. Signaling pathways involved in memory loss in AD are under intense …

Cognitive impairment and emotional disturbances in Alzheimer's disease (AD) result from
the degeneration of synapses and death of neurons in the limbic system and associated …

When properly controlled, Ca2+ fluxes across the plasma membrane and between
intracellular compartments play critical roles in fundamental functions of neurons, including …