[HTML] nih.gov

Metabolite levels in the brain reward pathway discriminate those who remain abstinent from those who resume hazardous alcohol consumption after treatment for …

TC Durazzo, V Pathak, S Gazdzinski, A Mon… - Journal of studies on …, 2010 - jsad.com
Objective: This study compared baseline metabolite levels in components of the brain
reward system among individuals who remained abstinent and those who resumed …
被引用次数：46 相关文章 所有 10 个版本
[PDF] academia.edu

Brain metabolite concentrations and neurocognition during short‐term recovery from alcohol dependence: preliminary evidence of the effects of concurrent chronic …

TC Durazzo, S Gazdzinski, JC Rothlind… - Alcoholism: Clinical …, 2006 - Wiley Online Library
Background: Longitudinal studies of brain tissue metabolite recovery in short‐term abstinent
alcoholics have primarily investigated the frontal lobes and cerebellum with variable results …
被引用次数：89 相关文章 所有 7 个版本
[PDF] academia.edu

Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics

J Wrase, F Schlagenhauf, T Kienast, T Wüstenberg… - Neuroimage, 2007 - Elsevier
OBJECTIVE: Alcohol dependence may be associated with dysfunction of mesolimbic
circuitry, such that anticipation of nonalcoholic reward fails to activate the ventral striatum …
被引用次数：595 相关文章 所有 18 个版本
[HTML] nih.gov

Brain metabolite levels in recently sober individuals with alcohol use disorder: Relation to drinking variables and relapse

NM Zahr, RA Carr, T Rohlfing, D Mayer… - Psychiatry Research …, 2016 - Elsevier
Magnetic resonance spectroscopy (MRS) studies in alcohol use disorder (AUD) typically
report lower levels of N-acetylaspartate (NAA) and choline-containing compounds (Cho) in …
被引用次数：28 相关文章 所有 7 个版本
[HTML] nih.gov

Intraindividual changes in brain GABA, glutamate, and glutamine during monitored abstinence from alcohol in treatment‐naive individuals with alcohol use disorder

JJ Prisciandaro, JP Schacht, AP Prescot… - Addiction …, 2020 - Wiley Online Library
Proton magnetic resonance spectroscopy (1H‐MRS) studies have demonstrated abnormal
levels of a variety of neurometabolites in treatment‐seeking individuals with moderate …
被引用次数：22 相关文章 所有 5 个版本
[HTML] nih.gov

Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: relationships to relapse and extended abstinence

TC Durazzo, D Tosun, S Buckley… - Alcoholism: Clinical …, 2011 - Wiley Online Library
Background: At least 60% of those treated for an alcohol use disorder will relapse. Empirical
study of the integrity of the brain reward system (BRS) is critical to understanding the …
被引用次数：279 相关文章 所有 11 个版本
[PDF] academia.edu

Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics

SM Grüsser, J Wrase, S Klein, D Hermann… - …, 2004 - Springer
Rationale Animal experiments have provided evidence that the striatum and medial
prefrontal cortex play a predominant role in the acquisition and maintenance of drug …
被引用次数：720 相关文章 所有 12 个版本
[HTML] nih.gov

Glutamate, GABA, and other cortical metabolite concentrations during early abstinence from alcohol and their associations with neurocognitive changes

A Mon, TC Durazzo, DJ Meyerhoff - Drug and alcohol dependence, 2012 - Elsevier
BACKGROUND: Little is known about the effects of alcohol dependence on cortical
concentrations of glutamate (Glu) or gamma aminobutyric acid (GABA). We used proton …
被引用次数：136 相关文章 所有 11 个版本
[HTML] nih.gov

Cortical metabolite alterations in abstinent cocaine and cocaine/alcohol‐dependent subjects: Proton magnetic resonance spectroscopic imaging

DJ Meyerhoff, C Bloomer, N Schuff, F Ezekiel… - Addiction …, 1999 - Wiley Online Library
Chronic abuse of cocaine or alcohol is associated with structural, neuropathological and
cognitive impairments that have been documented extensively. Little is known, however …
被引用次数：34 相关文章 所有 8 个版本
[PDF] researchgate.net

Brain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese‐enhanced magnetic resonance imaging

M Dudek, U Abo‐Ramadan, D Hermann… - Addiction …, 2015 - Wiley Online Library
The neuroanatomical and neurochemical basis of alcohol reward has been studied
extensively, but global alterations of neural activity in reward circuits during chronic alcohol …
被引用次数：41 相关文章 所有 9 个版本