Materials and Methods: Trabecular bone was obtained from 10 patients (four males, mean
age 76 years) with lower extremity osteoporotic fractures. MSCs were isolated by enzymatic …

Background Since the osteogenic potential of bone marrow derived mesenchymal stem
cells (BMSCs) becomes reduced with passage, establishment of culture condition that …

The osteogenic factors bone morphogenetic protein (BMP-7), platelet-derived growth factor
(PDGF)-BB, and fibroblast growth factor (FGF-2) regulate the recruitment of osteoprogenitor …

Bone marrow stroma contains multipotential mesenchymal progenitor cells which can
differentiate into osteoblastic cells; we refer to these cells as mesenchymal stem cells …

Basic fibroblast growth factor (bFGF) and bone morphogenetic protein-2 (BMP-2) are
actively pursued for stimulation of bone formation. To assess their promise for systemic …

Growth factors and mesenchymal stem cells (MSC) support consolidation of bone defects.
Bone Morphogenetic Protein-7 (BMP-7) has been used clinically and experimentally, but the …

The central role of bone morphogenetic proteins (BMPs) in the remodelling process of the
human skeleton has been identified in numerous experimental and clinical studies. BMPs …

Mesenchymal stem cells (MSCs) have the capabilities to proliferate and differentiate into
osteoblastic and chondrogenic lineages when stimulated with bone morphogenic proteins …

Bone mesenchymal stem cells (BMSCs) have been an area of interest in biomedical
research and tissue engineering due to their diverse differentiation abilities. In osteogenesis …

Although the action of bone morphogenetic protein (BMP) on osteoblast differentiation has
been extensively investigated, its effect on osteoclast differentiation remains unknown. In the …