Alginate protects NT2 neurons against H2O2-induced neurotoxicity

B Eftekharzadeh, F Khodagholi, A Abdi… - Carbohydrate …, 2010 - Elsevier
Increased oxidative stress is a widely accepted factor in the development and progression of
Alzheimer's disease. Here we introduced alginate–an antioxidant oligosaccharide–as a …

Alginate oligosaccharide protects against endoplasmic reticulum-and mitochondrial-mediated apoptotic cell death and oxidative stress

SK Tusi, L Khalaj, G Ashabi, M Kiaei, F Khodagholi - Biomaterials, 2011 - Elsevier
Oxidative stress is a major component of harmful cascades activated in neurodegenerative
disorders. We sought to elucidate possible effects of alginate oligosaccharide (AOS) on H 2 …

Retracted Article: Chitosan prevents oxidative stress-induced amyloid β formation and cytotoxicity in NT2 neurons: Involvement of transcription factors Nrf2 and NF-κB

F Khodagholi, B Eftekharzadeh, N Maghsoudi… - Molecular and cellular …, 2010 - Springer
Increased oxidative stress is a widely accepted factor in the development and progression of
Alzheimer's disease. Here, we introduce chitosan, an antioxidant oligosaccharide, as a …

Chitooligosaccharide-mediated neuroprotection is associated with modulation of Hsps expression and reduction of MAPK phosphorylation

G Joodi, N Ansari, F Khodagholi - International journal of biological …, 2011 - Elsevier
There is mounting evidence implicating the role of oxidative stress induced by reactive
oxygen species (ROS) in neurodegenerative disease, including Alzheimer's disease. In this …

Neuroprotective effect of Annona muricata-derived polysaccharides in neuronal HT22 cell damage induced by hydrogen peroxide

WS Kim, YE Kim, EJ Cho, EB Byun… - Bioscience …, 2020 - academic.oup.com
Crude extracts and phytochemical compounds derived from Annona muricata leaves have
been demonstrated to exert neuroprotective effects. However, the neuroprotective effects of …

Alginate-derived oligosaccharide inhibits neuroinflammation and promotes microglial phagocytosis of β-amyloid

R Zhou, XY Shi, DC Bi, WS Fang, GB Wei, X Xu - Marine drugs, 2015 - mdpi.com
Alginate from marine brown algae has been widely applied in biotechnology. In this work,
the effects of alginate-derived oligosaccharide (AdO) on lipopolysaccharide (LPS)/β-amyloid …

Catalpol attenuates the neurotoxicity induced by β-amyloid1–42 in cortical neuron–glia cultures

B Jiang, J Du, J Liu, YM Bao, LJ An - Brain research, 2008 - Elsevier
A glia-mediated inflammation plays an important role in the pathogenesis of Alzheimer's
disease (AD). In vitro, besides a direct neurotoxic effect on neurons, Aβ activates glia to …

The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde

P Sun, J Chen, J Li, M Sun, W Mo, K Liu… - … and alternative medicine, 2013 - Springer
Background Formaldehyde can induce misfolding and aggregation of Tau protein and β
amyloid protein, which are characteristic pathological features of Alzheimer's disease (AD) …

Characterization of lactic acid bacteria derived exopolysaccharides for use as a defined neuroprotective agent against amyloid beta1–42-induced apoptosis in SH …

S Sirin, B Aslim - Scientific Reports, 2020 - nature.com
Alzheimer's disease (AD) is a disease characterized by cerebral neuronal degeneration and
loss in a progressive manner. Amyloid beta (Aβ) in the brain is toxic to neurons, being a …

Protective effect of chitosan oligosaccharide against hydrogen peroxide-mediated oxidative damage and cell apoptosis via activating Nrf2/ARE signaling pathway

X Zhang, S Liang, X Gao, H Huang, F Lao, X Dai - Neurotoxicity Research, 2021 - Springer
Chitosan oligosaccharide (COS), hydrolyzed and deacetylated from chitosan, has been
reported to possess varieties of biological activities. Alzheimer's disease (AD) is a …