Borrelia burgdorferi, the agent of Lyme disease, is unusual as it contains free cholesterol
and cholesterol glycolipids. It is also susceptible to complement-independent bactericidal …

Borrelia burgdorferi contains unique cholesterol-glycolipid-rich lipid rafts that are associated
with lipoproteins. These complexes suggest the existence of macromolecular structures that …

Borrelia burgdorferi, the agent of Lyme disease, has cholesterol and cholesterol-glycolipids
that are essential for bacterial fitness, are antigenic, and could be important in mediating …

Lipid rafts in eukaryotic cells are sphingolipid and cholesterol-rich, ordered membrane
regions that have been postulated to play roles in many membrane functions, including …

The lack of methods for isolating Borrelia burgdorferi outer membranes (OMs) has hindered
efforts to characterize borrelial surface-exposed proteins. Here we isolated OMs by …

Lipid rafts are microdomains present in the membrane of eukaryotic organisms and bacterial
pathogens. They are characterized by having tightly packed lipids and a subset of specific …

Borrelia burgdorferi lipoproteins are 50-to 500-fold more active as cytokine inducers and B-
cell mitogens than Escherichia coli lipoproteins and synthetic peptides containing the …

The binding of Borrelia burgdorferi, the causative agent of Lyme disease, to
glycosphingolipids present in various types of cells was examined. B. burgdorferi bound …

Borrelia burgdorferi, the Lyme disease pathogen, dramatically alters its protein profile when
it is transmitted between ticks and mammals. Several differentially expressed proteins have …

Isolated outer membranes of Borrelia burgdorferi 297 were utilized to obtain partial amino
acid sequence information for a low-molecular-weight, outer membrane-associated …