Objective. To determine the effects of sodium oxybate (SXB) on sleep physiology and
sleep/wake-related symptoms in patients with fibromyalgia syndrome (FM). Methods. Of 304 …

Objective To evaluate the safety and efficacy of sodium oxybate for management of the
symptoms of fibromyalgia syndrome (FMS). Methods Patients with FMS (according to the …

This 14-week, phase 3, double-blind, randomized, controlled trial evaluated sodium oxybate
(SXB) 4.5 and 6g per night versus placebo in patients with fibromyalgia (FM). SXB is the …

OBJECTIVE: Fibromyalgia (FM) is associated with the sleep phenomenon of alpha intrusion,
and with low growth hormone secretion. Sodium oxybate has been shown to increase both …

Background Fibromyalgia is characterised by chronic musculoskeletal pain and multiple
symptoms including fatigue, multidimensional function impairment, sleep disturbance and …

Introduction: Gamma-hydroxybutyrate (GHB) is a short-chain fatty acid that is synthesized
within the CNS, mostly from its parent compound gamma amino butyric acid (GABA). GHB …

Fibromyalgia is a syndrome characterized by the presence of chronic widespread pain,
representing sensitization of the central nervous system. The pthophysiology of fibromyalgia …

Objective. To determine the effects of bedtime very low dose (VLD) cyclobenzaprine (CBP)
on symptoms and sleep physiology of patients with fibromyalgia (FM), unrefreshing sleep …

Objective This study is an examination of sleep, pain, depression, and physical functioning
at baseline and 1‐year followup among patients with fibromyalgia syndrome (FMS) …

Fibromyalgia is a chronic pain disorder characterized by widespread pain, stiffness,
insomnia, fatigue and distress. Several randomized controlled trials (RCTs) have shown …