Genomics of pulmonary arterial hypertension: implications for therapy
MW Geraci, TM Bull, RM Tuder - Heart failure clinics, 2010 - heartfailure.theclinics.com
The first descriptions of pulmonary arterial hypertension (PAH) have fascinated clinicians
and scientists since these brief initial descriptions. Despite significant advances in the …
and scientists since these brief initial descriptions. Despite significant advances in the …
[HTML][HTML] The role of genomics and genetics in pulmonary arterial hypertension
EM Swietlik, S Gräf, NW Morrell - Global Cardiology Science & …, 2020 - ncbi.nlm.nih.gov
Although pulmonary hypertension (PH) had been recognised for centuries, it was not until
the invention of cardiac catheterisation in the 1950s that enabled an accurate clinical …
the invention of cardiac catheterisation in the 1950s that enabled an accurate clinical …
Genetics and genomics of pulmonary arterial hypertension
NW Morrell, MA Aldred, WK Chung… - European …, 2019 - Eur Respiratory Soc
Since 2000 there have been major advances in our understanding of the genetic and
genomics of pulmonary arterial hypertension (PAH), although there remains much to …
genomics of pulmonary arterial hypertension (PAH), although there remains much to …
Genetics and genomics of pulmonary arterial hypertension
Major discoveries have been obtained within the last decade in the field of hereditary
predisposition to pulmonary arterial hypertension (PAH). Among them, the identification of …
predisposition to pulmonary arterial hypertension (PAH). Among them, the identification of …
[HTML][HTML] Translational Advances in the Field of Pulmonary Hypertension Molecular Medicine of Pulmonary Arterial Hypertension. From Population Genetics to …
An improved understanding of the molecular causes and modifiers of pulmonary arterial
hypertension (PAH) has emerged during the last several decades. However, the survival of …
hypertension (PAH) has emerged during the last several decades. However, the survival of …
Molecular medicine of pulmonary arterial hypertension: from population genetics to precision medicine and gene editing
An improved understanding of the molecular causes and modifiers of pulmonary arterial
hypertension (PAH) has emerged during the last several decades. However, the survival of …
hypertension (PAH) has emerged during the last several decades. However, the survival of …
Epigenetic mechanisms in pulmonary arterial hypertension: the need for global perspectives
P Chelladurai, W Seeger… - European Respiratory …, 2016 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a severe and progressive disease, characterised
by high pulmonary artery pressure that usually culminates in right heart failure. Recent …
by high pulmonary artery pressure that usually culminates in right heart failure. Recent …
[HTML][HTML] Mechanisms of disease: pulmonary arterial hypertension
RT Schermuly, HA Ghofrani, MR Wilkins… - Nature Reviews …, 2011 - nature.com
Our understanding of, and approach to, pulmonary arterial hypertension has undergone a
paradigm shift in the past decade. Once a condition thought to be dominated by increased …
paradigm shift in the past decade. Once a condition thought to be dominated by increased …
The genetics of pulmonary arterial hypertension
ED Austin, JE Loyd - Circulation research, 2014 - Am Heart Assoc
Pulmonary arterial hypertension (PAH) is a progressive and fatal disease for which there is
an ever-expanding body of genetic and related pathophysiological information on disease …
an ever-expanding body of genetic and related pathophysiological information on disease …
Molecular genetic framework underlying pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder typified by occlusion
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …