How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens
M Brigl, MB Brenner - Seminars in immunology, 2010 - Elsevier
Invariant natural killer T (iNKT) cells have evolved to recognize CD1d-presented lipid
antigens and are known to play important roles during infection with bacterial, viral …
antigens and are known to play important roles during infection with bacterial, viral …
Innate-like recognition of microbes by invariant natural killer T cells
M Kronenberg, Y Kinjo - Current opinion in immunology, 2009 - Elsevier
Invariant natural killer T cells (iNKT cells) express a restricted T cell antigen receptor (TCR)
repertoire and they respond rapidly to glycolipid antigens presented by CD1d. These …
repertoire and they respond rapidly to glycolipid antigens presented by CD1d. These …
Activation strategies for invariant natural killer T cells
AC Kohlgruber, CA Donado, NM LaMarche… - Immunogenetics, 2016 - Springer
Invariant natural killer T (iNKT) cells are a specialized T cell subset that plays an important
role in host defense, orchestrating both innate and adaptive immune effector responses …
role in host defense, orchestrating both innate and adaptive immune effector responses …
The response of CD1d-restricted invariant NKT cells to microbial pathogens and their products
L Van Kaer, VV Parekh, L Wu - Frontiers in immunology, 2015 - frontiersin.org
Invariant natural killer T (iNKT) cells become activated during a wide variety of infections.
This includes organisms lacking cognate CD1d-binding glycolipid antigens recognized by …
This includes organisms lacking cognate CD1d-binding glycolipid antigens recognized by …
Strategy of lipid recognition by invariant natural killer T cells:'one for all and all for one'
T Mallevaey, T Selvanantham - Immunology, 2012 - Wiley Online Library
Invariant natural killer T (iNKT) cells are evolutionarily conserved lipid‐reactive T cells that
bridge innate and adaptive immune responses. Despite a relatively restricted T‐cell receptor …
bridge innate and adaptive immune responses. Despite a relatively restricted T‐cell receptor …
Recognition of microbial glycolipids by natural killer T cells
T cells can recognize microbial antigens when presented by dedicated antigen-presenting
molecules. While peptides are presented by classical members of the major …
molecules. While peptides are presented by classical members of the major …
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions
PJ Brennan, M Brigl, MB Brenner - Nature Reviews Immunology, 2013 - nature.com
Invariant natural killer T (iNKT) cells exist in a'poised effector'state, which enables them to
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …
The role of invariant natural killer T cells in microbial immunity
Y Kinjo, N Kitano, M Kronenberg - Journal of Infection and Chemotherapy, 2013 - Springer
Invariant natural killer T cells (i NKT cells) are unique lymphocytes with characteristic
features, such as expression of an invariant T-cell antigen receptor (TCR) α-chain …
features, such as expression of an invariant T-cell antigen receptor (TCR) α-chain …
Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection
M Brigl, RVV Tatituri, GFM Watts, V Bhowruth… - Journal of Experimental …, 2011 - rupress.org
Invariant natural killer T cells (iNKT cells) are critical for host defense against a variety of
microbial pathogens. However, the central question of how iNKT cells are activated by …
microbial pathogens. However, the central question of how iNKT cells are activated by …
Functions of CD1d-restricted invariant natural killer T cells in antimicrobial immunity and potential applications for infection control
Y Kinjo, S Takatsuka, N Kitano, S Kawakubo… - Frontiers in …, 2018 - frontiersin.org
CD1d-restricted invariant natural killer T (i NKT) cells are innate-type lymphocytes that
express a T-cell receptor (TCR) containing an invariant α chain encoded by the Vα14 gene …
express a T-cell receptor (TCR) containing an invariant α chain encoded by the Vα14 gene …