Expression and subcellular localisation of poly (A)-binding proteins
H Burgess - 2010 - era.ed.ac.uk
Poly (A)-binding proteins (PABPs) are important regulators of mRNA translation and stability.
In mammals four cytoplasmic PABPs with a similar domain structure have been described …
In mammals four cytoplasmic PABPs with a similar domain structure have been described …
Poly (A)-binding proteins are required for diverse biological processes in metazoans
RWP Smith, TKP Blee, NK Gray - Biochemical Society …, 2014 - portlandpress.com
PABPs [poly (A)-binding proteins] bind to the poly (A) tail of eukaryotic mRNAs and are
conserved in species ranging from yeast to human. The prototypical cytoplasmic member …
conserved in species ranging from yeast to human. The prototypical cytoplasmic member …
Nuclear relocalisation of cytoplasmic poly (A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs
HM Burgess, WA Richardson… - Journal of cell …, 2011 - journals.biologists.com
Poly (A)-binding protein 1 (PABP1) has a fundamental role in the regulation of mRNA
translation and stability, both of which are crucial for a wide variety of cellular processes …
translation and stability, both of which are crucial for a wide variety of cellular processes …
Investigating the role of PABPC5 in mouse physiology
HD Gyurova - 2024 - era.ed.ac.uk
Poly (A)-binding proteins (PABPs) are a family of RNA-binding proteins involved in post-
transcriptional regulation. In mammals five PABPs have been identified, some widely …
transcriptional regulation. In mammals five PABPs have been identified, some widely …
The roles of cytoplasmic poly (A)-binding proteins in regulating gene expression: a developmental perspective
B Gorgoni, NK Gray - Briefings in Functional Genomics, 2004 - academic.oup.com
Abstract Poly (A)-binding proteins (PABPs) are central to the regulation of messenger RNA
(mRNA) translation and stability; however, the roles and contributions of different PABP …
(mRNA) translation and stability; however, the roles and contributions of different PABP …
The role of mammalian poly (A)-binding proteins in co-ordinating mRNA turnover
M Brook, NK Gray - Biochemical Society Transactions, 2012 - portlandpress.com
The function of cytoplasmic PABPs [poly (A)-binding proteins] in promoting mRNA
translation has been intensively studied. However, PABPs also have less clearly defined …
translation has been intensively studied. However, PABPs also have less clearly defined …
[HTML][HTML] Depletion of nuclear poly (A) binding protein PABPN1 produces a compensatory response by cytoplasmic PABP4 and PABP5 in cultured human cells
RB Bhattacharjee, J Bag - PloS one, 2012 - journals.plos.org
Background In vertebrates, poly (A) binding protein (PABP) is known to exist in five different
isoforms. PABPs are primarily cytosolic with the exception of the nuclear PABP (PABPN1) …
isoforms. PABPs are primarily cytosolic with the exception of the nuclear PABP (PABPN1) …
Poly (A)-binding proteins are functionally distinct and have essential roles during vertebrate development
B Gorgoni, WA Richardson… - Proceedings of the …, 2011 - National Acad Sciences
Translational control of many mRNAs in developing metazoan embryos is achieved by
alterations in their poly (A) tail length. A family of cytoplasmic poly (A)-binding proteins …
alterations in their poly (A) tail length. A family of cytoplasmic poly (A)-binding proteins …
Poly (A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2
M Yoshida, K Yoshida, G Kozlov, NS Lim… - The EMBO …, 2006 - embopress.org
The poly (A)‐binding protein (PABP) is a unique translation initiation factor in that it binds to
the mRNA 3′ poly (A) tail and stimulates recruitment of the ribosome to the mRNA at the …
the mRNA 3′ poly (A) tail and stimulates recruitment of the ribosome to the mRNA at the …
Poly (A)-binding proteins and mRNA localization: who rules the roost?
NK Gray, L Hrabálková, JP Scanlon… - Biochemical Society …, 2015 - portlandpress.com
RNA-binding proteins are often multifunctional, interact with a variety of protein partners and
display complex localizations within cells. Mammalian cytoplasmic poly (A)-binding proteins …
display complex localizations within cells. Mammalian cytoplasmic poly (A)-binding proteins …