All tissues in the mature vertebrate body are derived from one of three cell populations
specified early in development, the ectoderm, mesoderm and endoderm. Mesodermal cells …

The process of gastrulation is highly conserved across vertebrates on both the genetic and
morphological levels, despite great variety in embryonic shape and speed of development …

Abstract The Nodal, BMP, and FGF signaling pathways have all been implicated in
mesoderm formation. My studies reveal the partially redundant, overlapping roles that these …

Vertebrate mesoderm induction is one of the classical problems in developmental biology.
Various developmental biology approaches, particularly in Xenopus and zebrafish, have …

In amniotes, mesoderm and endoderm arise during gastrulation, the process that derives the
three primary germ layers and establishes the basic body plan of the embryo. However, in …

The mesoderm arises prior to gastrulation as a ring at the equator of the embryo (Fig. lA).
This ring of cells sits on top of an extra embryonic structure called the yolk syncytial layer …

The tight spatiotemporal coordination of signaling activity determining embryo patterning
and the physical processes driving embryo morphogenesis renders embryonic development …

The epithelial to mesenchymal transition (EMT) is an essential process that occurs
repeatedly during embryogenesis whereby stably adherent cells convert to an actively …

The formation of the vertebrate body plan begins with the differentiation of cells into three
germ layers: ectoderm, mesoderm and endoderm. Cells in the endoderm give rise to the …

The segregation of cells into germ layers is one of the earliest events in the establishment of
cell fate in the embryo. In the zebrafish, endoderm and mesoderm are derived from cells that …