Bio-molecular architects: a scaffold provided by the C-terminal domain of eukaryotic RNA polymerase II
M Zhang, GN Gill, Y Zhang - Nano reviews, 2010 - Taylor & Francis
In eukaryotic cells, the transcription of genes is accurately orchestrated both spatially and
temporally by the C-terminal domain of RNA polymerase II (CTD). The CTD provides a …
temporally by the C-terminal domain of RNA polymerase II (CTD). The CTD provides a …
Modifications of RNA polymerase II CTD: Connections to the histone code and cellular function
R Srivastava, SH Ahn - Biotechnology advances, 2015 - Elsevier
At the onset of transcription, many protein machineries interpret the cellular signals that
regulate gene expression. These complex signals are mostly transmitted to the …
regulate gene expression. These complex signals are mostly transmitted to the …
Simplicity is the ultimate sophistication—crosstalk of post-translational modifications on the rna polymerase ii
The highly conserved C-terminal domain (CTD) of the largest subunit of RNA polymerase II
comprises a consensus heptad (Y 1 S 2 P 3 T 4 S 5 P 6 S 7) repeated multiple times …
comprises a consensus heptad (Y 1 S 2 P 3 T 4 S 5 P 6 S 7) repeated multiple times …
[HTML][HTML] Proteomics studies of the interactome of RNA polymerase II C-terminal repeated domain
G Pineda, Z Shen, CP de Albuquerque, E Reynoso… - BMC research …, 2015 - Springer
Abstract Background Eukaryotic RNA polymerase II contains a C-terminal repeated domain
(CTD) consisting of 52 consensus heptad repeats of Y 1 S 2 P 3 T 4 S 5 P 6 S 7 that mediate …
(CTD) consisting of 52 consensus heptad repeats of Y 1 S 2 P 3 T 4 S 5 P 6 S 7 that mediate …
Structural motifs for CTD kinase specificity on RNA polymerase II during eukaryotic transcription
The phosphorylation states of RNA polymerase II coordinate the process of eukaryotic
transcription by recruitment of transcription regulators. The individual residues of the …
transcription by recruitment of transcription regulators. The individual residues of the …
RNA polymerase II carboxy-terminal domain with multiple connections
EJ Cho - Experimental & Molecular Medicine, 2007 - nature.com
The largest subunit of eukaryotic RNA polymerase II contains a unique domain at its carboxy-
terminus, which is referred to as the carboxy-terminal domain (CTD). The CTD is made up of …
terminus, which is referred to as the carboxy-terminal domain (CTD). The CTD is made up of …
Comparative genomics and evolution of proteins associated with RNA polymerase II C-terminal domain
Z Guo, JW Stiller - Molecular biology and evolution, 2005 - academic.oup.com
The C-terminal domain (CTD) of the largest subunit of RNA polymerase II provides an
anchoring point for a wide variety of proteins involved in mRNA synthesis and processing …
anchoring point for a wide variety of proteins involved in mRNA synthesis and processing …
[HTML][HTML] The RNA polymerase II carboxy-terminal domain (CTD) code
D Eick, M Geyer - Chemical reviews, 2013 - ACS Publications
The smallest viable unit of life is the cell. From bacteria to mammals, all cells use the same
nucleic acid-based universal code for the maintenance and inheritance of genetic …
nucleic acid-based universal code for the maintenance and inheritance of genetic …
The RNA polymerase II CTD coordinates transcription and RNA processing
The C-terminal domain (CTD) of the RNA polymerase II largest subunit consists of multiple
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …
Transcription by RNA polymerase II and the CTD-chromatin crosstalk
The epigenetic phenomenon is known to derive the phenotypic variation of an organism
through an interconnected cellular network of histone modifications, DNA methylation and …
through an interconnected cellular network of histone modifications, DNA methylation and …