[图书][B] Improved crystallographic methods for RNA Polymerase II complexes using intrinsic anomalous scattering

PA Meyer - 2010 - search.proquest.com
Abstract RNA Polymerase II (Pol II) is the central enzyme in eukaryotic mRNA transcription.
In recent years, structural studies have provided insights into the mechanism of Pol II. A full …

[HTML][HTML] Structure of the 12-subunit RNA polymerase II refined with the aid of anomalous diffraction data

PA Meyer, P Ye, MH Suh, M Zhang, J Fu - Journal of biological chemistry, 2009 - ASBMB
RNA polymerase II (Pol II) is the central enzyme of eukaryotic gene expression machinery.
Complete definition of the three-dimensional structure of Pol II is essential for understanding …

RNA polymerase II structure: from core to functional complexes

P Cramer - Current opinion in genetics & development, 2004 - Elsevier
New structural studies of RNA polymerase II (Pol II) complexes mark the beginning of a
detailed mechanistic analysis of the eukaryotic mRNA transcription cycle. Crystallographic …

Structural biology of RNA polymerase II transcription: 20 years on

S Osman, P Cramer - Annual Review of Cell and …, 2020 - annualreviews.org
Gene transcription by RNA polymerase II (Pol II) is the first step in the expression of the
eukaryotic genome and a focal point for cellular regulation during development …

Structure–function analysis of RNA polymerases I and III

M Werner, P Thuriaux, J Soutourina - Current opinion in structural biology, 2009 - Elsevier
Recent advances in elucidating the structure of yeast Pol I and III are based on a
combination of X-ray crystal analysis, electron microscopy and homology modelling. They …

[PDF][PDF] Structure-function analysis of RNA polymerase II

E Lehmann - 2011 - edoc.ub.uni-muenchen.de
During this work structural and functional analysis of RNA polymerase II (Pol II) was
conducted. RNA polymerase II is the enzyme performing DNA transcription by synthesising …

Structural studies on RNA polymerase I transcription

C Fernández-Tornero, E Torreira, J Louro, O Calvo… - 2015 - digital.csic.es
Biosynthesis of the eukaryotic ribosome starts with ribosomal RNA production by RNA
polymerase I (Pol I), a process that is critical to regulate cell growth and proliferation. We …

Structural basis of RNA polymerase II substrate specificity and catalysis

D Wang, DA Bushnell, KD Westover, CD Kaplan… - 2007 - Wiley Online Library
The fundamental mechanism of transcription is conserved among cellular RNA
polymerases. New structures of RNA polymerase II (pol II) transcribing complexes reveal a …

Structure of eukaryotic RNA polymerases

P Cramer, KJ Armache, S Baumli, S Benkert… - Annu. Rev …, 2008 - annualreviews.org
The eukaryotic RNA polymerases Pol I, Pol II, and Pol III are the central multiprotein
machines that synthesize ribosomal, messenger, and transfer RNA, respectively. Here we …

An alternative RNA polymerase I structure reveals a dimer hinge

D Kostrewa, CD Kuhn, C Engel… - … Section D: Biological …, 2015 - journals.iucr.org
RNA polymerase I (Pol I) is the central, 14-subunit enzyme that synthesizes the ribosomal
RNA (rRNA) precursor in eukaryotic cells. The recent crystal structure of Pol I at 2.8 Å …