Current tissue engineering approaches for tendon defects require improved biomaterials to
balance microstructural and mechanical design criteria. Collagen-glycosaminoglycan (CG) …

We investigated whether tissue constructs resembling structural and mechanical properties
of the myocardium would induce mesenchymal stem cells (MSCs) to differentiate into a …

In the present work, the two-photon polymerization (2PP) technique was applied to develop
precisely defined biodegradable 3D tissue engineering scaffolds. The scaffolds were …

Stem cells are central to developing new treatment options for tissue regeneration and
constructing controllable models for biological research. Bioengineered cell culture …

The severe shortage of available donor hearts necessitates the development of other
options for heart replacement. Recent results underline the promise of the decellularized …

Rationale: Cardiac tissue engineering should provide “realistic” in vitro heart muscle models
and surrogate tissue for myocardial repair. For either application, engineered myocardium …

A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed
thermoplastic shrink film to create tunable multiscaled alignment" wrinkles". Using this …

Synthetic biomaterials serve as a cornerstone in the development of clinically focused
regenerative medicine therapies that aim to reduce suffering and prolong life. Recent …

A key challenge in tissue engineering is overcoming cell death in the scaffold interior due to
the limited diffusion of oxygen and nutrients therein. We here hypothesize that immobilizing …

Heart failure remains the leading cause of morbidity and mortality. Recently, it was reported
that the adult heart has intrinsic regenerative capabilities, prompting a great wave of …