Complex interactions between genes and environmental factors may result in destruction of
the body's own cells and tissues by the immune system, ie autoimmunity. Rheumatoid …

The present invention is directed to antibodies and binding fragments thereof, which bind
with high affinity and speci ficity to human P-selectin glycoprotein ligand 1 (PSGL-1) and …

Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease primarily affecting
the joints. 1 The disease affects approximately 1% of the population worldwide. 2 RA occurs …

The human immune system is a highly evolved system that plays a central role in health and
disease. Unders-tanding the aging-associated immune changes is critical to explaining both …

Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without
powerful treatment, may lead to irreversible joint damage. During the past decade, anti …

概要 ミクリッツ病 (Mikulicz'disease: MD) は, 涙腺や唾液の腫脹を特徴とし, 病理組織学的類似性
から, シェーグレン症候群 (Sjögren's syndrome: SS) の一亜型 として認識されてきた. しかし, MD …

Rheumatoid arthritis (RA) is a systemic, chronic inflammatory disease that is manifested as a
destructive polyarthritis in association with serological evidence of autoreactivity. It is …