Importance of PIKKs in NF-κB activation by genotoxic stress
H Sabatel, C Pirlot, J Piette, Y Habraken - Biochemical pharmacology, 2011 - Elsevier
Alteration of the genome integrity leads to the activation of a vast network of cellular
responses named “DNA damage response”. Three kinases from the phosphoinositide 3 …
responses named “DNA damage response”. Three kinases from the phosphoinositide 3 …
Poly (ADP-ribosyl) ation affects stabilization of Che-1 protein in response to DNA damage
MG Bacalini, D Di Lonardo, A Catizone, F Ciccarone… - DNA repair, 2011 - Elsevier
Poly (ADP-ribose) polymerase 1 (PARP-1) catalyzes a post-translational modification that
plays a crucial role in coordinating the signalling cascade in response to stress stimuli …
plays a crucial role in coordinating the signalling cascade in response to stress stimuli …
Mass spectrometry-based functional proteomics of poly (ADP-ribose) polymerase-1
E Pic, JP Gagné, GG Poirier - Expert review of proteomics, 2011 - Taylor & Francis
PARP-1 is an abundant nuclear protein that plays an essential role in the regulation of many
genome integrity and chromatin-based processes, such as DNA repair, replication or …
genome integrity and chromatin-based processes, such as DNA repair, replication or …
Frameshift mutations of poly (adenosine diphosphate-ribose) polymerase genes in gastric and colorectal cancers with microsatellite instability
MS Kim, CH An, SS Kim, NJ Yoo, SH Lee - Human pathology, 2011 - Elsevier
Poly (adenosine diphosphate-ribose) polymerases consist of 16 members that modify
nuclear proteins by building adenosine diphosphate-ribose polymers. Poly (adenosine …
nuclear proteins by building adenosine diphosphate-ribose polymers. Poly (adenosine …
Role of Apoptotic Proteins in REC‐2006 Mediated Radiation Protection in Hepatoma Cell Lines
The present study was carried out to evaluate the role of apoptotic proteins in REC‐2006‐
mediated radiation protection in hepatoma cell lines. REC‐2006 treatment 2 h before …
mediated radiation protection in hepatoma cell lines. REC‐2006 treatment 2 h before …
Inhibiteurs de la PARP: des avancées significatives dans le traitement des cancers
F Dantzer, G Noel, V Schreiber - Bulletin du cancer, 2011 - Elsevier
Résumé La poly (ADP-ribosyl) ation est une modification post-traductionnelle de protéines
nucléaires médiée par les poly (ADP-ribose) polymérases (PARPs). En réponse aux agents …
nucléaires médiée par les poly (ADP-ribose) polymérases (PARPs). En réponse aux agents …
[PDF][PDF] The potential of the PARP-1 inhibitor, AG014699, in human cancers defective in homologous recombination DNA repair
Y Drew - University of New Castle Upon Tyne, New Castle Upon …, 2011 - core.ac.uk
The aims of this study were to undertake the first comprehensive in vitro, in vivo and clinical
investigation into the effects of the PARP-1 inhibitor, AG014699, in human cancers defective …
investigation into the effects of the PARP-1 inhibitor, AG014699, in human cancers defective …
[PDF][PDF] НАДФ увеличивает уровень фосфорилированного гистона H2AX в сердце мышей после рентгеновского облучения
ДВ Фирсанов, АВ Кропотов, ВМ Михайлов - Цитология, 2011 - tsitologiya.incras.ru
Фосфорилирование вариантного корового гистона Н2Ах происходит в мегабазных
доменах хромаr тина вокруг двухнитевых разрывов дНК (дР дНК). Эта модификация …
доменах хромаr тина вокруг двухнитевых разрывов дНК (дР дНК). Эта модификация …
Exogenous NADP increases the level of histone H2AX phosphorylation in mouse heart cells after ionizing radiation
DV Firsanov, AV Kropotov, VM Mikhailov - Cell and Tissue Biology, 2011 - Springer
Phosphorylation of replacement histone H2AX occurs in megabase chromatin domains
around DNA double-strand breaks (DSBs), and this modification called γ-H2AX can be used …
around DNA double-strand breaks (DSBs), and this modification called γ-H2AX can be used …
[PDF][PDF] EXPLOITING THE SYNTHETIC LETHAL INTERACTION OF ATM AND PARP
CT Williamson - 2011 - prism.ucalgary.ca
DNA is under constant assault from both endogenous and exogenous processes. As a
result, maintaining genomic stability is one of the most important functions of the cell. Failure …
result, maintaining genomic stability is one of the most important functions of the cell. Failure …