Functional and biochemical studies of CD9 in fibrosarcoma cell line

S Chen, Y Sun, Z Jin, X Jing - Molecular and cellular biochemistry, 2011 - Springer
CD9, a member of the tetraspanin family, plays important roles in a variety of cell activities.
Fibrosarcoma is a malignant tumor that arises from fibroblasts. Low CD9 expression is found …

The tetraspanin CD81 mediates the growth and metastases of human osteosarcoma

N Mizoshiri, T Shirai, R Terauchi, S Tsuchida, Y Mori… - Cellular Oncology, 2019 - Springer
Purpose CD81 is a member of the tetraspanin family of membrane proteins. Recently, it has
been shown that CD81 may be involved in cancer cell proliferation and metastasis. As yet …

Over-expression of CD9 does not affect in vivo tumorigenic or metastatic properties of human prostate cancer cells

V Zvieriev, JC Wang, M Chevrette - Biochemical and biophysical research …, 2005 - Elsevier
Expression of tetraspanin CD9 protein is downregulated in many tumors. CD9 over-
expression also reduces the tumorigenicity of some human cancer cells. Here, we …

Tetraspanin CD9 promotes the invasive phenotype of human fibrosarcoma cells via upregulation of matrix metalloproteinase-9

MJ Herr, J Kotha, N Hagedorn, B Smith, LK Jennings - PloS one, 2013 - journals.plos.org
Tumor cell metastasis, a process which increases the morbidity and mortality of cancer
patients, is highly dependent upon matrix metalloproteinase (MMP) production. Small …

CD9 expression in gastric cancer and its significance

H Hori, S Yano, K Koufuji, J Takeda… - Journal of Surgical …, 2004 - Elsevier
BACKGROUND: The tetraspanin transmembrane protein CD9 is known to be involved in
cell adhesion, proliferation, and cell motility. Previous studies have reported that reduced …

The tetraspanin CD9 modulates epidermal growth factor receptor signaling in cancer cells

Y Murayama, Y Shinomura, K Oritani… - Journal of cellular …, 2008 - Wiley Online Library
CD9 is a member of the tetraspanins, and has been shown to be involved in a variety of
cellular activities such as migration, proliferation, and adhesion. In addition, it has been …

The tetraspanin CD9 inhibits the proliferation and tumorigenicity of human colon carcinoma cells

S Ovalle, MD GutiérrezLópez, N Olmo… - … journal of cancer, 2007 - Wiley Online Library
The implication of the tetraspanin CD9 in cancer has received much recent attention and an
inverse correlation between CD9 expression and the metastatic potential and cancer …

Expression of tetraspanins in human lung cancer cells: frequent downregulation of CD9 and its contribution to cell motility in small cell lung cancer

T Funakoshi, I Tachibana, Y Hoshida, H Kimura… - Oncogene, 2003 - nature.com
Small cell lung cancer (SCLC) invades locally and metastasizes distantly extremely early
when compared with nonsmall cell lung cancer (NSCLC). The underlying molecular …

Tetraspanin CD81 promotes tumor growth and metastasis by modulating the functions of T regulatory and myeloid-derived suppressor cells

F Vences-Catalán, R Rajapaksa, MK Srivastava… - Cancer research, 2015 - AACR
Tumor cells counteract innate and adaptive antitumor immune responses by recruiting
regulatory T cells (Treg) and innate myeloid-derived suppressor cells (MDSC), which …

Involvement of CD24 in multiple cancer related pathways makes it an interesting new target for cancer therapy

S Eyvazi, B Kazemi, S Dastmalchi… - Current cancer drug …, 2018 - ingentaconnect.com
CD24 (cluster of differentiation 24) is a small heavy glycosylated protein, which is
overexpressed in many cancer and some cancer stem cells and is associated with the …