Les problèmes de toxicomanie sont très communs chez les schizophrènes. L'administration
chronique d'antipsychotiques pourrait être impliquée dans cette cooccurrence en induisant …

Drug abuse and addiction are excessively common in schizophrenia. Chronic antipsychotic
treatment might contribute to this comorbidity by inducing supersensitivity within the brain's …

Chronic exposure to antipsychotic medications can persistently change brain dopamine
systems. Most studies on the functional significance of these neural changes have focused …

It has been suggested that the high prevalence of drug abuse in schizophrenics is related to
chronic treatment with typical neuroleptics and dopaminergic supersensitivity that develops …

Comorbid drug abuse in schizophrenia has been consistently reported as high, with
estimates ranging between 10–70%. Comorbid addictive states in schizophrenia are …

Antipsychotic drugs are widely used in the treatment of schizophrenia. While their effects are
considered to be due to a modulation of dopaminergic and serotonergic signaling, little is …

Partial agonists such as aripiprazole are often used in addition to a full antagonist such as
amisulpride, risperidone or olanzapine in an attempt to mitigate side-effects such as …

Beaucoup de personnes consomment des drogues d'abus de façon récréative ou
expérimentale dans leur vie, mais peu d'entre elles développent une toxicomanie. Nous …

Objective The purpose of the study was to compare antipsychotic monotherapies in terms of
time to discontinuation in a sample of schizophrenia patients followed‐up for 36 months …

Rationale Clozapine and the “atypical” antipsychotics are less prone than neuroleptics to
induce extrapyramidal motor effects, worsening of the negative symptoms of schizophrenia …