Myocardial infarction results in extensive cardiomyocyte death which can lead to fatal
arrhythmias or congestive heart failure. Delivery of stem cells to repopulate damaged …

Despite numerous efforts to generate mature human pluripotent stem cell-derived
cardiomyocytes (hPSC-CMs), cells often remain immature, electrically isolated, and may not …

For cardiac tissue engineering, much attention has been given to the artificial cardiac
microenvironment in which anisotropic design of scaffold and extracellular matrix (ECM) are …

Engineering native‐like myocardial muscle, recapitulating its fibrillar organization and
mechanical behavior is still a challenge. This study reports the rational design and …

Tissue engineering (TE) combines cells, scaffolds, and growth factors to assemble functional
tissues for repair or replacement of tissues and organs. Cardiac TE is focused on developing …

Myocardial infarction remains the leading cause of death in the western world. Since the
heart has limited regenerative capabilities, several cardiac tissue engineering (CTE) …

Current limitations in cardiac tissue engineering revolve around the inability to fully
recapitulate the structural organization and mechanical environment of native cardiac tissue …

Cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs) show great
potential for engineering myocardium to study cardiac disease and create regenerative …

Electrospun nanofiber constructs represent a promising alternative for mimicking the natural
extracellular matrix in vitro and have significant potential for cardiac patch applications …

Embryonic stem cells (ESCs) are an important source of cardiomyocytes for regenerating
injured myocardium. The successful use of ESC‐derived cardiomyocytes in cardiac tissue …