Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms.

GE Miller, E Chen, KJ Parker - Psychological bulletin, 2011 - psycnet.apa.org
Among people exposed to major psychological stressors in early life, there are elevated
rates of morbidity and mortality from chronic diseases of aging. The most compelling data …

A developmental pathway from early life stress to inflammation: The role of negative health behaviors

EB Raposa, JE Bower, CL Hammen… - Psychological …, 2014 - journals.sagepub.com
Early life stressors are associated with elevated inflammation, a key physiological risk factor
for disease. However, the mechanisms by which early stress leads to inflammation remain …

Mechanisms linking early life stress to adult health outcomes

SE Taylor - Proceedings of the National Academy of …, 2010 - National Acad Sciences
Research relating stress to health has progressed from anecdotal evidence in the 1930s
and 1940s to complex multivariate models that identify underlying longitudinal mechanisms …

Stressful early life experiences and immune dysregulation across the lifespan

CP Fagundes, R Glaser, JK Kiecolt-Glaser - Brain, behavior, and immunity, 2013 - Elsevier
There is considerable evidence that stressful early life events influence a variety of physical
health problems later in life. Childhood adversity has been linked to elevated rates of …

Early-life stress and adult inflammation

CP Fagundes, B Way - Current Directions in Psychological …, 2014 - journals.sagepub.com
The origins of modern psychology are deeply rooted in the notion that stressful early-life
experiences negatively impact people's mental health. Emerging work in the field of health …

Early-life adversity and physical and emotional health across the lifespan: A neuroimmune network hypothesis

R Nusslock, GE Miller - Biological psychiatry, 2016 - Elsevier
Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …

Early-life stress: from neuroendocrine mechanisms to stress-related disorders

P Pervanidou, GP Chrousos - Hormone research in paediatrics, 2018 - karger.com
Stress exposure is highly prevalent in the general population; however, the experience of
stress during vulnerable periods of development has substantial and permanent effects on …

Adolescence: a central event in shaping stress reactivity

RD Romeo - Developmental Psychobiology: The Journal of the …, 2010 - Wiley Online Library
The magnitude and duration of the hormonal stress response change dramatically
throughout an organism's lifespan. Although much is known about the factors that modulate …

Testing the biological embedding hypothesis: Is early life adversity associated with a later proinflammatory phenotype?

KB Ehrlich, KM Ross, E Chen… - Development and …, 2016 - cambridge.org
Accumulating evidence suggests that the experience of early life adversity is a risk factor for
a range of poor outcomes across development, including poor physical health in adulthood …

Three common assumptions about inflammation, aging, and health that are probably wrong

TW McDade - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Chronic inflammation contributes to the onset and progression of cardiovascular disease
and other degenerative diseases of aging. But does it have to? This article considers the …