Signaling by the tumor necrosis factor receptor superfamily in B‐cell biology and disease
RC Rickert, J Jellusova, AV Miletic - Immunological reviews, 2011 - Wiley Online Library
Members of the tumor necrosis factor receptor superfamily (TNFRSF) participate prominently
in B‐cell maturation and function. In particular, B‐cell activating factor belonging to the TNF …
in B‐cell maturation and function. In particular, B‐cell activating factor belonging to the TNF …
An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates …
MD Morrison, W Reiley, M Zhang, SC Sun - Journal of Biological Chemistry, 2005 - ASBMB
BAFF receptor (BAFFR) is a member of the TNF receptor (TNFR) superfamily that regulates
the survival and maturation of B cells. BAFFR exerts its signaling function by inducing …
the survival and maturation of B cells. BAFFR exerts its signaling function by inducing …
TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor
Tumor necrosis factor receptor-associated factors 2 and 3 (TRAF2 and TRAF3) were shown
to function in a cooperative and nonredundant manner to suppress nuclear factor-κB2 (NF …
to function in a cooperative and nonredundant manner to suppress nuclear factor-κB2 (NF …
Act1, a negative regulator in CD40-and BAFF-mediated B cell survival
Y Qian, J Qin, G Cui, M Naramura, EC Snow, CF Ware… - Immunity, 2004 - cell.com
TNF receptor (TNFR) superfamily members, CD40, and BAFFR play critical roles in B cell
survival and differentiation. Genetic deficiency in a novel adaptor molecule, Act1, for CD40 …
survival and differentiation. Genetic deficiency in a novel adaptor molecule, Act1, for CD40 …
TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-κB, elk-1, c-Jun …
A Hatzoglou, J Roussel, MF Bourgeade… - The Journal of …, 2000 - journals.aai.org
BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is
preferentially expressed in mature B lymphocytes. Previously, we reported in a human …
preferentially expressed in mature B lymphocytes. Previously, we reported in a human …
Regulatory roles of the tumor necrosis factor receptor BCMA
CM Coquery, LD Erickson - Critical Reviews™ in Immunology, 2012 - dl.begellhouse.com
ABSTRACT B cell maturation antigen (BCMA) is a tumor necrosis family receptor (TNFR)
member that is predominantly expressed on terminally differentiated B cells and, upon …
member that is predominantly expressed on terminally differentiated B cells and, upon …
The biochemistry and biology of BAFF, APRIL and their receptors
SL Kalled, C Ambrose, YM Hsu - B Cell Trophic Factors and B Cell …, 2005 - karger.com
The tumor necrosis factor (TNF) family of related receptors and ligands contains a rich
collection of molecules that are important players in a broad spectrum of biological systems …
collection of molecules that are important players in a broad spectrum of biological systems …
Cracking the BAFF code
F Mackay, P Schneider - Nature reviews immunology, 2009 - nature.com
The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling
B-cell activation factor from the tumor necrosis factor family (BAFF) is a key survival factor
during B-cell maturation—a delicate immune checkpoint for B cells. Excessive BAFF …
during B-cell maturation—a delicate immune checkpoint for B cells. Excessive BAFF …
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling
JM Hildebrand, Z Luo, MK Manske… - Journal of Experimental …, 2010 - rupress.org
The cytokine B cell activating factor (BAFF) and its receptor, BAFF receptor (BAFF-R),
modulate signaling cascades critical for B cell development and survival. We identified a …
modulate signaling cascades critical for B cell development and survival. We identified a …