Broad epigenetic signature of maternal care in the brain of adult rats
Background Maternal care is associated with long-term effects on behavior and epigenetic
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of …
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of …
Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus
M Suderman, PO McGowan, A Sasaki… - Proceedings of the …, 2012 - National Acad Sciences
Early life experience is associated with long-term effects on behavior and epigenetic
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of …
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of …
Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat
Increased levels of pup licking/grooming and arched-back nursing by rat mothers over the
first week of life alter the epigenome at a glucocorticoid receptor gene promoter in the …
first week of life alter the epigenome at a glucocorticoid receptor gene promoter in the …
Maternal imprints and the origins of variation
FA Champagne - Hormones and behavior, 2011 - Elsevier
The non-genomic transmission of maternal behavior from one generation to the next
illustrates the pervasive influence of maternal care on offspring development and the high …
illustrates the pervasive influence of maternal care on offspring development and the high …
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life
ICG Weaver, FA Champagne, SE Brown… - Journal of …, 2005 - Soc Neuroscience
Stress responses in the adult rat are programmed early in life by maternal care and
associated with epigenomic marking of the hippocampal exon 17 glucocorticoid receptor …
associated with epigenomic marking of the hippocampal exon 17 glucocorticoid receptor …
Epigenetic programming by maternal behavior
ICG Weaver, N Cervoni, FA Champagne… - Nature …, 2004 - nature.com
Here we report that increased pup licking and grooming (LG) and arched-back nursing
(ABN) by rat mothers altered the offspring epigenome at a glucocorticoid receptor (GR) gene …
(ABN) by rat mothers altered the offspring epigenome at a glucocorticoid receptor (GR) gene …
Epigenetic Programming by Maternal Behavior and Pharmacological Intervention Nature Versus Nurture: Let's Call The Whole Thing Off
ICG Weaver - Epigenetics, 2007 - Taylor & Francis
The nature of maternal care that an infant receives can effect the child's emotional and
cognitive development, which is endured into adulthood. Similarly, maternal behavior in …
cognitive development, which is endured into adulthood. Similarly, maternal behavior in …
Maternal separation is associated with strain‐specific responses to stress and epigenetic alterations to Nr3c1, Avp, and Nr4a1 in mouse
Stressful events early in life have been widely linked to behavioral phenotypes and have
been implicated in the development of psychiatric disorders. Using a maternal separation …
been implicated in the development of psychiatric disorders. Using a maternal separation …
Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood
ICG Weaver, MJ Meaney… - Proceedings of the …, 2006 - National Acad Sciences
Early-life experience has long-term consequences on behavior and stress responsivity of
the adult. We previously proposed that early-life experience results in stable epigenetic …
the adult. We previously proposed that early-life experience results in stable epigenetic …
Epigenetic mechanisms mediating the long-term effects of maternal care on development
FA Champagne, JP Curley - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
The long-term consequences of early environmental experiences for development have
been explored extensively in animal models to better understand the mechanisms mediating …
been explored extensively in animal models to better understand the mechanisms mediating …