MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Biogenesis of mammalian microRNAs: a global view

P Graves, Y Zeng - Genomics, Proteomics and Bioinformatics, 2012 - academic.oup.com
Abstract MicroRNAs (miRNAs) are approximately 22-nucleotide-long non-coding RNAs that
are important regulators of gene expression in eukaryotes. miRNAs are first transcribed as …

[HTML][HTML] MicroRNAs: processing, maturation, target recognition and regulatory functions

GC Shukla, J Singh, S Barik - Molecular and cellular pharmacology, 2011 - ncbi.nlm.nih.gov
The remarkable discovery of small noncoding microRNAs (miRNAs) and their role in
posttranscriptional gene regulation have revealed another fine-tuning step in the expression …

A developmental view of microRNA function

Y Zhao, D Srivastava - Trends in biochemical sciences, 2007 - cell.com
MicroRNAs (miRNAs) are genomically encoded small non-coding RNAs that regulate flow of
genetic information by controlling translation or stability of mRNAs. Recent recognition that …

Biological functions of microRNAs: a review

Y Huang, XJ Shen, Q Zou, SP Wang, SM Tang… - Journal of physiology …, 2011 - Springer
MicroRNAs (miRNAs) are a recently discovered family of endogenous, noncoding RNA
molecules approximately 22 nt in length. miRNAs modulate gene expression post …

Functional aspects of animal microRNAs

AE Williams - Cellular and molecular life sciences, 2008 - Springer
MicroRNAs (miRNAs) are a recently discovered family of small regulatory molecules that
function by modulating protein production. There are approximately 500 known mammalian …

MicroRNAs: a new class of gene regulators

DJ Guarnieri, RJ DiLeone - Annals of medicine, 2008 - Taylor & Francis
Elucidation of the molecular basis of disease depends upon continued progress in defining
the mechanisms by which genomic information is encoded and expressed. Transcription …

Analysis of microRNA knockouts in mice

CY Park, YS Choi, MT McManus - Human molecular genetics, 2010 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that act as potent regulators of gene
expression. The discovery of miRNAs with specific temporal and spatial expression patterns …

MicroRNA biogenesis: regulating the regulators

EF Finnegan, AE Pasquinelli - Critical reviews in biochemistry and …, 2013 - Taylor & Francis
MicroRNAs (miRNAs) function as 21–24 nucleotide guide RNAs that use partial base-
pairing to recognize target messenger RNAs and repress their expression. As a large …

Mechanisms of control of microRNA biogenesis

BN Davis-Dusenbery, A Hata - The journal of biochemistry, 2010 - academic.oup.com
MicroRNAs (miRNAs) are a class of∼ 22 nt non-coding RNAs that control diverse biological
functions in animals, plants and unicellular eukaryotes by promoting degradation or …