Regulation of cyclooxygenase‐2 expression in human bladder epithelial cells infected with type I fimbriated uropathogenic E. coli

TC Chen, JP Tsai, HJ Huang, CC Teng… - Cellular …, 2011 - Wiley Online Library
The type 1 fimbriae of uropathogenic Escherichia coli (UPEC) have been described as
important for the establishment of bladder infections and urinary tract infections (UTI) …

[HTML][HTML] Difference in the regulation of IL-8 expression induced by uropathogenic E. coli between two kinds of urinary tract epithelial cells

KW Tsai, HT Lai, TC Tsai, YC Wu, YT Yang… - Journal of biomedical …, 2009 - Springer
Bacterial adherence to epithelial cells is a key virulence trait of pathogenic bacteria. The
type 1 fimbriae and the P-fimbriae of uropathogenic Escherichia coli (UPEC) have both been …

Suppression of Bladder Epithelial Cytokine Responses by Uropathogenic Escherichia coli

DA Hunstad, SS Justice, CS Hung, SR Lauer… - Infection and …, 2005 - Am Soc Microbiol
Urinary tract infections are most commonly caused by uropathogenic strains of Escherichia
coli (UPEC), which invade superficial bladder epithelial cells via a type 1 pilus-dependent …

Modulation of Host Innate Immune Response in the Bladder by Uropathogenic Escherichia coli

BK Billips, SG Forrestal, MT Rycyk… - Infection and …, 2007 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC), the most frequent cause of urinary tract infection
(UTI), is associated with an inflammatory response which includes the induction of …

Uropathogenic escherichia coli: interactions with bladder epithelium

SJ Hultgren - Urology, 2001 - goldjournal.net
Bladder smooth muscle cells (SMC) play an important role in the progression of bladder
deterioration after outlet obstruction. Altered mechanical environment within the obstructed …

Molecular Basis of Uropathogenic Escherichia coli Evasion of the Innate Immune Response in the Bladder

BK Billips, AJ Schaeffer, DJ Klumpp - Infection and immunity, 2008 - Am Soc Microbiol
In the urinary tract, the innate immune system detects conserved bacterial components and
responds to infection by activating the proinflammatory transcription factor NF-κB, resulting …

[HTML][HTML] Uropathogenic Escherichia coli invades bladder epithelial cells by activating kinase networks in host cells

WJ Kim, AE Shea, JH Kim, Y Daaka - Journal of Biological Chemistry, 2018 - ASBMB
Uropathogenic Escherichia coli (UPEC) is the causative bacterium in most urinary tract
infections (UTIs). UPEC cells adhere to and invade bladder epithelial cells (BECs) and …

P‐fimbriae trigger mucosal responses to Escherichia coli in the human urinary tract

B Wullt, G Bergsten, H Connell, P Röllano… - Cellular …, 2001 - Wiley Online Library
Uropathogenic Escherichia coli elicit a host response that determines the severity of urinary
tract infection (UTI). Specific adherence mechanisms allow the bacteria to initiate this …

Bacterial invasion augments epithelial cytokine responses to Escherichia coli through a lipopolysaccharide-dependent mechanism

JD Schilling, MA Mulvey, CD Vincent… - The Journal of …, 2001 - journals.aai.org
One mechanism of initiating innate host defenses against uropathogenic Escherichia coli
(UPEC) is the production of cytokines by bladder epithelial cells; however, the means by …

Forced COX-2 expression induces PGE2 and invasion in immortalized urothelial cells

J Gee, IL Lee, HB Grossman, AL Sabichi - Urologic Oncology: Seminars …, 2008 - Elsevier
OBJECTIVES: Cyclooxygenase 2 (COX-2) is aberrantly expressed in multiple tumor types
including bladder cancer and is associated with enhanced growth, resistance to apoptosis …