Extinction is the reduction in drug seeking when the contingency between drug seeking
behavior and the delivery of drug reward is broken. Here, we investigated a role for the …

The nucleus accumbens shell (AcbSh) is required to inhibit drug seeking after extinction
training. Conversely, the lateral hypothalamus (LH), which receives projections from AcbSh …

Environmental contexts associated with drug use promote craving in humans and drug‐
seeking in animals. We hypothesized that the basolateral amygdala (BLA) itself as well as …

The contexts where drugs are self‐administered have important control over relapse and
extinction of drug‐seeking behavior. The nucleus accumbens shell (AcbSh) is essential to …

The consolidation of cue–cocaine associations and extinction learning (ie cue–no cocaine
associations) into long‐term memory probably regulates the long‐lasting control of …

We investigated the impact of cocaine-and amphetamine-regulated transcript (CART) in the
nucleus accumbens shell (AcbSh) on context-induced reinstatement of alcoholic beer …

Drug-associated conditioned cues promote subjects to recall drug reward memory, resulting
in drug-seeking and reinstatement. A consolidated memory becomes unstable after recall …

Repetitive drug taking induces neural long-lasting changes and results in compulsive drug-
seeking behavior which may arise from enduring drug memory that impairs cognitive control …

Previous research from our laboratory has implicated the basolateral amygdala (BLA)
complex in the acquisition and consolidation of cue–cocaine associations, as well as …

The functional integrity of the nucleus accumbens (NAC) core and shell is necessary for
contextual cocaine‐seeking behavior in the reinstatement animal model of drug relapse; …