Host cell and bacterial factors determine severity and duration of infections. To allow for
bacteria pathogenicity and persistence, bacteria have developed mechanisms that modify …

Patients suffering from recurrent urinary tract infections (UTIs) may be maintained on
antibiotic prophylaxis, or even treated by surgery. However, there are no biological data on …

Objective: This study was undertaken to investigate whether hypermethylation in p16INK4a
gene promoter could serve as plasma biomarker of bladder cancer. Methods and Patients …

Expression of the imprinted CDKN1C gene at chromosome 11p15. 5 encoding the cell cycle
inhibitor p57KIP2 is disturbed in Beckwith‐Wiedemann syndrome and in several human …

Promoter hypermethylation is one of the putative mechanisms underlying the inactivation of
negative cell-cycle regulators. We examined whether the methylation status of p16INK4a …

Uropathogenic Escherichia coli (UPEC), the principal cause of urinary tract infection in
women, colonizes the gut as well as the genitourinary tract. Studies of mice inoculated with …

Purpose: Many scientific evidences suggested that the methylation of p16INK4a (p16) was
associated with bladder cancer, but some existing studies have yielded inconclusive results …

PURPOSE:: We elucidated the significance of aberrant DNA methylation on multiple CpG
islands and its correlation with DNA methyltransferase DNMT1 protein expression during …

Purpose: There are significant differences in reported frequencies, modes of inactivation,
and clinical significance of CDKN2A in urothelial cell carcinoma (UCC). We aimed to …

DNA hypermethylation has emerged as a molecular biomarker for the evaluation of cancer
diagnosis and prognosis. We define a methylation signature of bladder cancer and evaluate …