The prototypic autoimmune disease, SLE, is known to be associated with polyclonal B cell
hyperreactivity. Developing an understanding of the complex nature of human B cell …

Autoreactive B cells and plasma cells appear to be of central importance in the
pathogenesis of systemic lupus erythematosus (SLE) characterized by a plethora of …

A variety of cell surface markers are being used to identify B cell subpopulations in
peripheral blood. Currently at least eight subpopulationshave been identified. Analyses of …

Peripheral blood B cells that were actively proliferating, those actively secreting
immunoglobulin, and those expressing an early activation marker, Ba antigens, on the …

B cells are critical players in the orchestration of properly regulated immune responses,
normally providing protective immunity without autoimmunity. Balance in the B cell …

Understanding antibody repertoires and in particular, the properties and fates of B cells
expressing potentially pathogenic antibodies is critical to define the mechanisms underlying …

B lymphocytes from patients with systemic lupus erythematosus (SLE) are hyperactive and
produce autoantibodies. Several B cell phenotype characteristics such as the expansion of …

In patients with active systemic lupus erythematosus (SLE), a marked B lymphocytopenia
was identified that affected CD19+/CD27− naive B cells more than CD19+/CD27+ memory B …

Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity | Nature
Immunology Skip to main content Thank you for visiting nature.com. You are using a browser …

B cells in human and murine systemic lupus erythematosus : Current Opinion in
Rheumatology B cells in human and murine systemic lupus erythematosus : Current …