Interleukin‐1β stimulates stromal‐derived factor‐1α expression in human subacromial bursa

TA Blaine, MA Cote, A Proto… - Journal of …, 2011 - Wiley Online Library
Chemokines produced by synoviocytes of the subacromial bursa are up‐regulated in
subacromial bursitis and rotator cuff disease. We hypothesized that SDF‐1α production in …

Stromal cell‐derived factor 1 (SDF‐1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti‐inflammatory agents

YS Kim, LU Bigliani, M Fujisawa… - Journal of …, 2006 - Wiley Online Library
Several studies have demonstrated that inflammation in the subacromial bursa is an
important component in the pathogenesis of impingement syndrome. We have …

Increased IL‐1β expression and myofibroblast recruitment in subacromial bursa is associated with rotator cuff lesions with shoulder stiffness

JY Ko, FS Wang, HY Huang, CJ Wang… - Journal of …, 2008 - Wiley Online Library
We evaluated whether proinflammatory cytokine expression and myofibroblast recruitment
in subacromial bursa was linked to rotator cuff lesions with shoulder stiffness. We analyzed …

IL-1β mediates NGF and COX-2 expression through transforming growth factor-activating kinase 1 in subacromial bursa cells derived from rotator cuff tear patients

N Nagura, K Uchida, T Kenmoku, G Inoue… - Journal of Orthopaedic …, 2019 - Elsevier
Abstract Background Increased interleukin (IL)-1β expression in the subacromial bursa
(SAB) is associated with severe pain in rotator cuff tears (RCTs). Additionally, transforming …

[PDF][PDF] Immunolocalization of cytokines and growth factors in subacromial bursa of rotator cuff tear patients

H Sakai, K Fujita, Y Sakai, K Mizuno - Kobe Journal of Medical Sciences, 2001 - Citeseer
Inflammation in the subacromial bursa causes pain in patients suffering from rotator cuff tear,
with this long-lasting inflammation leading to fibrosis and thickening of the subacromial …

The molecular pathophysiology of subacromial bursitis in rotator cuff disease

TA Blaine, YS Kim, I Voloshin, D Chen… - Journal of Shoulder and …, 2005 - Elsevier
Little information exists on the molecular and biochemical pathophysiology of subacromial
bursitis and rotator cuff disease. We investigated the pattern of expression of cytokines …

Interleukin‐1‐induced subacromial synovitis and shoulder pain in rotator cuff diseases

M Gotoh, K Hamada, H Yamakawa… - …, 2001 - academic.oup.com
Objective. To determine the relationship between the expression of interleukin‐1 β (IL‐1 β)
and IL‐1 receptor antagonists (IL‐1ra) in the subacromial bursa and shoulder pain in rotator …

Stromal cell‐derived factor‐1/CXCR4 promotes IL‐6 production in human synovial fibroblasts

HT Chen, HK Tsou, CJ Hsu, CH Tsai… - Journal of cellular …, 2011 - Wiley Online Library
The production of chemokine stromal cell‐derived factor (SDF)‐1 is significantly higher in
synovial fluid of patients with osteoarthritis (OA). IL‐6 is a multifunctional cytokine that plays …

[HTML][HTML] Pro-Resolving Mediators in Rotator Cuff Disease: How Is the Bursa Involved?

F Klatte-Schulz, N Bormann, A Bonell, J Al-Michref… - Cells, 2023 - mdpi.com
So far, tendon regeneration has mainly been analyzed independent from its adjacent
tissues. However, the subacromial bursa in particular appears to influence the local …

The interaction between human rotator cuff tendon and subacromial bursal tissue in co-culture

LM Tamburini, BJ Levy, MB McCarthy… - Journal of Shoulder and …, 2021 - Elsevier
Background The role of subacromial bursa in rotator cuff pathology is unclear. Along with
recognized inflammatory potential, current data demonstrate the presence of mesenchymal …