Conversion of linoleic acid and alpha‐linolenic acid to long‐chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of …

RA Gibson, B Muhlhausler… - Maternal & child …, 2011 - Wiley Online Library
Over the past two decades, there has been a marked shift in the fatty acid composition of the
diets of industrialized nations towards increased intake of the n‐6 fatty acid linoleic acid (LA …

The role of long chain polyunsaturated fatty acids (LCPUFA) in neonatal nutrition

RA Gibson, M Makrides - Acta Paediatrica, 1998 - Wiley Online Library
Exciting new research has shown that both preterm and term infants can actively convert the
essential fatty acids linoleic acid (LA, 18: 2n‐6) and α‐linolenic acid (ALA, 18: 3n‐3) to long …

Long‐chain polyunsaturated fatty acids and development of human infants

SE Carlson - Acta Paediatrica, 1999 - Wiley Online Library
Human infants require n‐6 and n‐3 long‐chain polyunsaturated fatty acids (LCPUFA),
derivatives of the essential fatty acids, linoleate (n‐6) and linolenate (n‐3), for growth and …

The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations

B Koletzko, E Lien, C Agostoni, H Böhles, C Campoy… - 2008 - degruyter.com
This paper reviews current knowledge on the role of the long-chain polyunsaturated fatty
acids (LC-PUFA), docosahexaenoic acid (DHA, C22: 6n-3) and arachidonic acid (AA, 20: 4n …

Perinatal supply and metabolism of long‐chain polyunsaturated fatty acids: importance for the early development of the nervous system

E Larque, H Demmelmair… - Annals of the New York …, 2002 - Wiley Online Library
The long‐chain polyunsaturated fatty acids, arachidonic (AA) and docosahexaenoic acid
(DHA), are essential structural lipid components of biomembranes. During pregnancy, long …

α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans

JT Brenna, N Salem Jr, AJ Sinclair… - … leukotrienes and essential …, 2009 - Elsevier
Blood levels of polyunsaturated fatty acids (PUFA) are considered biomarkers of status.
Alpha-linolenic acid, ALA, the plant omega-3, is the dietary precursor for the long-chain …

α‐Linolenic acid metabolism in adult humans: the effects of gender and age on conversion to longer‐chain polyunsaturated fatty acids

GC Burdge, PC Calder - European Journal of Lipid Science …, 2005 - Wiley Online Library
This review summarises and evaluates current knowledge of α‐linolenic acid (αLNA)
metabolism in adult humans. The principal biological role of αLNA appears to be as a …

Current information and Asian perspectives on long-chain polyunsaturated fatty acids in pregnancy, lactation, and infancy: systematic review and practice …

B Koletzko, CCM Boey, C Campoy… - Annals of Nutrition and …, 2014 - karger.com
Abstract The Early Nutrition Academy supported a systematic review of human studies on
the roles of pre-and postnatal long-chain polyunsaturated fatty acids (LC-PUFA) published …

Long chain polyunsaturated fatty acids (LC‐PUFA) and perinatal development

B Koletzko, C Agostoni, SE Carlson… - Acta …, 2001 - Wiley Online Library
This paper reports on the conclusions of a workshop on the role of long chain
polyunsaturated fatty acids (LC‐PUFA) in maternal and child health The attending …

Essential fatty acids in early life: structural and functional role

R Uauy, P Mena, C Rojas - Proceedings of the Nutrition Society, 2000 - cambridge.org
Essential fatty acids (EFA) are structural components of all tissues and are indispensable for
cell membrane synthesis; the brain, retina and other neural tissues are particularly rich in …