Gene expression and biological pathways in tissue of men with prostate cancer in a randomized clinical trial of lycopene and fish oil supplementation

MJM Magbanua, R Roy, EV Sosa, V Weinberg… - PloS one, 2011 - journals.plos.org
Background Studies suggest that micronutrients may modify the risk or delay progression of
prostate cancer; however, the molecular mechanisms involved are poorly understood. We …

Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer

JM Chan, V Weinberg, MJ Magbanua, E Sosa… - Cancer Causes & …, 2011 - Springer
Background Nutritional factors are associated with reduced risk of prostate cancer
progression, yet mechanisms remain unclear. We examined the effects of lycopene and fish …

Dietary lycopene, angiogenesis, and prostate cancer: a prospective study in the prostate-specific antigen era

K Zu, L Mucci, BA Rosner, SK Clinton… - Journal of the …, 2014 - academic.oup.com
Background The role of lycopene in prostate cancer prevention remains controversial. We
examined the associations between dietary lycopene intake and prostate cancer, paying …

Lycopene and vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model

U Siler, L Barella, V Spitzer, J Schnorr… - The FASEB …, 2004 - Wiley Online Library
Epidemiological studies have consistently associated high intakes of lycopene or vitamin E
with a reduced prostate cancer risk. Both compounds were tested in the MatLyLu Dunning …

Lycopene reduced gene expression of steroid targets and inflammatory markers in normal rat prostate

A Herzog, U Siler, V Spitzer, N Seifert… - The FASEB …, 2005 - Wiley Online Library
Epidemiological evidence links consumption of lycopene, the red carotenoid of tomato, to
reduced prostate cancer risk. We investigated the effect of lycopene in normal prostate …

Increased dietary and circulating lycopene are associated with reduced prostate cancer risk: a systematic review and meta-analysis

JL Rowles, KM Ranard, JW Smith, R An… - Prostate cancer and …, 2017 - nature.com
Background: Prostate cancer (PCa) is the fifth leading cause of cancer-related deaths
worldwide. Many epidemiological studies have investigated the association between …

Effects of lycopene supplementation in patients with localized prostate cancer

O Kucuk, FH Sarkar, Z Djuric, W Sakr… - Experimental …, 2002 - journals.sagepub.com
Epidemiological studies have shown an inverse association between dietary intake of
lycopene and prostate cancer risk. We conducted a clinical trial to investigate the biological …

[HTML][HTML] Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA

I Paur, W Lilleby, SK Bøhn, E Hulander, W Klein… - Clinical Nutrition, 2017 - Elsevier
Background & aims The effect of lycopene-containing foods in prostate cancer development
remains undetermined. We tested whether a lycopene-rich tomato intervention could reduce …

Lycopene effects contributing to prostate health

K Wertz - Nutrition and cancer, 2009 - Taylor & Francis
Epidemiological evidence links lycopene consumption with decreased prostate cancer risk.
Several signaling pathways have been identified as players in prostate cancer development …

Low prostate concentration of lycopene is associated with development of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia

S Mariani, L Lionetto, M Cavallari, A Tubaro… - International journal of …, 2014 - mdpi.com
Prostate cancer (PC) is a frequent male malignancy and represents the second most
diagnosed cancer in men. Since pre-cancerous lesions, ie, the high-grade prostatic …