The mechanistic link between obese parents and obese offspring and the relative role of
genes, and a shared environment is not completely understood. Animal models help us to …

The incidence of obesity and overweight has reached epidemic proportions in the
developed world as well as in those countries transitioning to first world economies, and this …

There is now clear evidence from population-based and experimental animal studies that
maternal obesity and maternal overnutrition, particularly excessive intake of high-fat and …

Animal models of maternal high fat diet (HFD) demonstrate perturbed offspring metabolism
although the effects differ markedly between models. We assessed studies investigating …

Modern lifestyle has resulted in an increase in the prevalence of obesity and its
comorbidities in pregnant women and the young population. It has been well established …

The incidence of metabolic disease, including type 2 diabetes and obesity, has increased to
epidemic levels in recent years. A growing body of evidence suggests that the intrauterine …

Aims/hypothesis Maternal obesity is associated with an increased risk of obesity and
impaired glucose homeostasis in offspring. However, it is not known whether a gestational …

Abstract Background/Objectives The current obesity epidemic has spurred exploration of the
developmental origin of adult heath and disease. A mother's dietary choices and health can …

Significant alterations in maternal nutrition may induce long‐term metabolic consequences
in offspring, in particular obesity and leptin and insulin resistance. Although maternal …

New Findings What is the topic of this review? Observational studies have highlighted the
association of increasing maternal body mass index with offspring adiposity and the …