The impact of obesity on egg quality

SH Purcell, KH Moley - Journal of assisted reproduction and genetics, 2011 - Springer
Obesity in women is a concern in many countries. This causes numerous health issues;
however, this review focuses on the impact of obesity on women's reproduction, and in …

Evidence that obesity alters the quality of oocytes and embryos

RL Robker - Pathophysiology, 2008 - Elsevier
Infertility is more common in overweight and obese women, with reproductive impairments
occurring at many levels of the hypothalamic-ovarian-uterine axis. These impairments lead …

The impact of obesity on oocytes: evidence for lipotoxicity mechanisms

LLY Wu, RJ Norman, RL Robker - Reproduction, Fertility and …, 2011 - CSIRO Publishing
Obesity can have detrimental effects on pregnancy rates in natural conceptions and also in
women undergoing IVF or intracytoplasmic sperm injection (ICSI). This review summarises …

[HTML][HTML] Obesity and female infertility: potential mediators of obesity's impact

DE Broughton, KH Moley - Fertility and sterility, 2017 - Elsevier
The worldwide upward trend in obesity has been dramatic, now affecting more than 20% of
American women of reproductive age. Obesity is associated with many adverse maternal …

Obesity and oocyte quality: significant implications for ART and emerging mechanistic insights

MB Gonzalez, RL Robker, RD Rose - Biology of reproduction, 2022 - academic.oup.com
The prevalence of obesity in adults worldwide, and specifically in women of reproductive
age, is concerning given the risks to fertility posed by the increased risk of type 2 diabetes …

Maternal obesity: A potential disruptor of female fertility and current interventions to reduce associated risks

T Muhammad, Y Wan, Y Lv, H Li, W Naushad… - Obesity …, 2023 - Wiley Online Library
Currently, obesity has achieved epidemic levels in reproductive‐aged women with a myriad
of consequences. Obesity is susceptible to several reproductive complications that …

[PDF][PDF] The adverse effects of obesity on reproduction

JE Norman - Reproduction, 2010 - researchgate.net
Obesity (defined as a body mass index (BMI) of R30 kg/m 2) is perhaps the major health
challenge facing resource-rich countries. Obesity is a major cause of ill health and mortality …

Human embryos from overweight and obese women display phenotypic and metabolic abnormalities

C Leary, HJ Leese, RG Sturmey - Human reproduction, 2015 - academic.oup.com
STUDY QUESTION Is the developmental timing and metabolic regulation disrupted in
embryos from overweight or obese women? SUMMARY ANSWER Oocytes from overweight …

Adverse effects of obesity and/or high-fat diet on oocyte quality and metabolism are not reversible with resumption of regular diet in mice

KA Reynolds, AL Boudoures, MMY Chi… - Reproduction …, 2015 - CSIRO Publishing
Obesity adversely affects reproduction and results in oocyte defects in both mice and
humans. In the present study we used a mouse model to examine whether the adverse …

Inflammatory pathways linking obesity and ovarian dysfunction

RL Robker, LLY Wu, X Yang - Journal of reproductive immunology, 2011 - Elsevier
This review summarizes some of the recent advances in obesity research and describes
how we and others have built upon these findings to better understand the impact of obesity …