Regenerative cardiovascular medicine is the frontline of 21st-century health care. Cell
therapy trials using bone marrow progenitor cells documented that the approach is feasible …

Cell therapy is a promising option for treating ischemic diseases and heart failure. Bone
marrow-derived vasculogenic cells, including progenitor cells and proangiogenic cells, have …

Although definition and mechanistic understanding of pro-angiogenic progenitor cells
remains unsatisfactory, general agreement highlights their role in regenerative process …

Stem or progenitor cell–based strategies to combat ischemic heart disease and myocardial
infarction, whether autologous transplantation or stimulation of resident populations, not only …

Stem cell biology holds great promise for a new era of cell-based therapy, sparking
considerable interest among scientists, clinicians, and their patients. However, the …

Across biomedicine, there is a major drive to develop stem cell (SC) treatments for
debilitating diseases. Most effective treatments restore an embryonic phenotype to adult …

Stem cells in adult organs reside in specialized niches that regulate their proliferation and
differentiation. Investigations during the last few years have unveiled a regulatory role for …

Stem cells contribute to innate healing and harbor a promising role for regenerative
medicine. Stem cell banking through long-term storage of different stem cell platforms …

Stem cell and regenerative approaches that might rejuvenate the heart have immense
intuitive appeal for the public and scientific communities. Hopes were fueled by initial …

In the past decade, substantial evidence supports the paradigm that stem cells exert their
reparative and regenerative effects, in large part, through the release of biologically active …