[HTML][HTML] The Phenotypic Radiation Resistance of CD44+/CD24−or low Breast Cancer Cells Is Mediated through the Enhanced Activation of ATM Signaling

H Yin, J Glass - PloS one, 2011 - journals.plos.org
Cancer initiating cells (CIC) are stem-like cells. CIC may contribute not only to the initiation
of cancer but also to cancer recurrence because of the resistance of CIC both to …

Forced extinction of CD24 stem‐like breast cancer marker alone promotes radiation resistance through the control of oxidative stress

J Bensimon, D Biard, V Paget, M Goislard… - Molecular …, 2016 - Wiley Online Library
Along with CD44, CD24 is a key marker of breast cancer stem cells (CSCs), frequently
defined by CD24−/CD44+ labeling. Among all phenotypes classically attributed to breast …

The Response of CD24 −/low /CD44 + Breast Cancer–Initiating Cells to Radiation

TM Phillips, WH McBride… - Journal of the National …, 2006 - academic.oup.com
Background: If cancer arises and is maintained by a small population of cancer-initiating
cells within every tumor, understanding how these cells react to cancer treatment will …

CD24−/low stem-like breast cancer marker defines the radiation-resistant cells involved in memorization and transmission of radiation-induced genomic instability

J Bensimon, S Altmeyer-Morel, H Benjelloun… - Oncogene, 2013 - nature.com
A growing body of evidence attributes properties of chemo-and/or radiation-resistance to
cancer stem cells (CSCs). Moreover, non-targeted delayed effects such as genomic …

[HTML][HTML] Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44+/CD24−/low Stem Cell Phenotype

X Gao, BJ Sishc, CB Nelson, P Hahnfeldt… - Frontiers in …, 2016 - frontiersin.org
The enrichment of putative CD44+/CD24−/low breast stem cell populations following
exposure to ionizing radiation (IR) has been ascribed to their inherent radioresistance and …

[HTML][HTML] Senescence evasion by MCF-7 human breast tumor-initiating cells

F Karimi-Busheri, A Rasouli-Nia, JR Mackey… - Breast Cancer …, 2010 - Springer
Introduction A subpopulation of cancer cells, tumor-initiating cells, is believed to be the
driving force behind tumorigenesis and resistance to radiation and chemotherapy. The …

[HTML][HTML] Breast cancer stem cell-like cells generated during TGFβ-induced EMT are radioresistant

J Konge, F Leteurtre, M Goislard, D Biard… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Failure of conventional antitumor therapy is commonly associated with cancer stem cells
(CSCs), which are often defined as inherently resistant to radiation and chemotherapeutic …

[HTML][HTML] CD146 interaction with integrin β1 activates LATS1-YAP signaling and induces radiation-resistance in breast cancer cells

Y Liang, X Zhou, Q Xie, H Sun, K Huang, H Chen… - Cancer Letters, 2022 - Elsevier
Radiotherapy is an indispensable modality in comprehensive treatment of breast cancer.
However, inherent or acquired radiation resistance of tumors compromises the efficacy of …

[HTML][HTML] Survival and self-renewing capacity of breast cancer initiating cells during fractionated radiation treatment

C Lagadec, E Vlashi, L Della Donna, YH Meng… - Breast cancer …, 2010 - Springer
Introduction Recent data indicate a hierarchical organization of many solid cancers,
including breast cancer, with a small number of cancer initiating cells (CICs) that have the …

Focal adhesion kinase and Wnt signaling regulate human ductal carcinoma in situ stem cell activity and response to radiotherapy

KE Williams, NJ Bundred, G Landberg, RB Clarke… - Stem …, 2015 - academic.oup.com
Cancer stem cells (CSCs) can avoid or efficiently repair DNA damage from radio and
chemotherapy, which suggests they play a role in disease recurrence. Twenty percentage of …