[HTML][HTML] Initiation but no execution-modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis-a potential role for heat shock protein 70

D Moodley, GM Mody, AA Chuturgoon - Journal of Inflammation, 2011 - Springer
Background Rheumatoid arthritis (RA) is a chronic autoimmune disease, which causes
synovial damage. Persistence of lymphocyte infiltrates in the rheumatoid synovium has been …

The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases

CM Cuda, RM Pope, H Perlman - Nature Reviews Rheumatology, 2016 - nature.com
Rheumatoid arthritis affects nearly 1% of the world's population and is a debilitating
autoimmune condition that can result in joint destruction. During the past decade …

Apoptotic regulators and RA

J Hutcheson, H Perlman - Current Rheumatology Reviews, 2008 - ingentaconnect.com
Although the etiology of rheumatoid arthritis (RA) is currently unknown, the disease is
mediated by chronic inflammation within the joint, characterized by leukocyte recruitment …

Apoptosis in rheumatoid arthritis: friend or foe

H Liu, RM Pope - Rheumatic Disease Clinics, 2004 - rheumatic.theclinics.com
Apoptosis is an evolutionarily conserved, multistep process by which the cell undergoes an
orderly demise. In contrast to cells undergoing necrosis, the contents of those undergoing …

Apoptotic cell clearance components in inflammatory arthritis

K Schneider, S Arandjelovic - Immunological Reviews, 2023 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease of the synovial joints that
affects~ 1% of the human population. Joint swelling and bone erosion, hallmarks of RA …

Apoptosis as a therapeutic tool in rheumatoid arthritis

RM Pope - Nature Reviews Immunology, 2002 - nature.com
Rheumatoid arthritis (RA) is a chronic inflammatory synovitis that is dominated by the
presence of macrophages, lymphocytes and synovial fibroblasts, which leads to the …

Intracellular apoptotic pathways: a potential target for reducing joint damage in rheumatoid arthritis

B Williams, A Dharmapatni, T Crotti - Inflammation Research, 2018 - Springer
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that results in both
local and systemic bone erosion, causing significant joint deformities and functional …

[HTML][HTML] Programmed cell death in rheumatoid arthritis peripheral blood T-cell subpopulations determined by laser scanning cytometry

P Szodoray, S Jellestad, B Nakken, JG Brun… - Laboratory …, 2003 - Elsevier
Because peripheral blood mononuclear cells play an important role in the perpetuation of
the autoimmune process in rheumatoid arthritis (RA) and because the maintenance of these …

The role of apoptosis in rheumatoid arthritis

H Liu, RM Pope - Current opinion in pharmacology, 2003 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease, which results in inflammation of
the synovial lining and destruction of the adjacent bone and cartilage. Synovial …

Apomodulation as a novel therapeutic concept for the regulation of apoptosis in rheumatoid synoviocytes

T Kobayashi, K Okamoto, T Kobata… - Current opinion in …, 1999 - journals.lww.com
Fas-mediated apoptosis is observed in synoviocytes of patients with rheumatoid arthritis
(RA). This process may be involved in the pathophysiology of RA. We have recently found …