Alginate oligosaccharide protects against endoplasmic reticulum-and mitochondrial-mediated apoptotic cell death and oxidative stress

SK Tusi, L Khalaj, G Ashabi, M Kiaei, F Khodagholi - Biomaterials, 2011 - Elsevier
Oxidative stress is a major component of harmful cascades activated in neurodegenerative
disorders. We sought to elucidate possible effects of alginate oligosaccharide (AOS) on H 2 …

Alginate protects NT2 neurons against H2O2-induced neurotoxicity

B Eftekharzadeh, F Khodagholi, A Abdi… - Carbohydrate …, 2010 - Elsevier
Increased oxidative stress is a widely accepted factor in the development and progression of
Alzheimer's disease. Here we introduced alginate–an antioxidant oligosaccharide–as a …

[HTML][HTML] Alginate-derived oligosaccharide inhibits neuroinflammation and promotes microglial phagocytosis of β-amyloid

R Zhou, XY Shi, DC Bi, WS Fang, GB Wei, X Xu - Marine drugs, 2015 - mdpi.com
Alginate from marine brown algae has been widely applied in biotechnology. In this work,
the effects of alginate-derived oligosaccharide (AdO) on lipopolysaccharide (LPS)/β-amyloid …

Alginate oligosaccharide alleviates myocardial reperfusion injury by inhibiting nitrative and oxidative stress and endoplasmic reticulum stress-mediated apoptosis

JJ Guo, FQ Xu, YH Li, J Li, X Liu, XF Wang… - Drug Design …, 2017 - Taylor & Francis
Alginate oligosaccharide (AOS) has recently demonstrated the ability to protect against
acute doxorubicin cardiotoxicity and neurodegenerative disorders by inhibiting oxidative …

Retracted Article: Chitosan prevents oxidative stress-induced amyloid β formation and cytotoxicity in NT2 neurons: Involvement of transcription factors Nrf2 and NF-κB

F Khodagholi, B Eftekharzadeh, N Maghsoudi… - Molecular and cellular …, 2010 - Springer
Increased oxidative stress is a widely accepted factor in the development and progression of
Alzheimer's disease. Here, we introduce chitosan, an antioxidant oligosaccharide, as a …

[HTML][HTML] Neuroprotective effects of ganoderma lucidum polysaccharides against oxidative stress-induced neuronal apoptosis

X Sun, Y Liao, W Li, L Guo - Neural regeneration research, 2017 - journals.lww.com
Ganoderma lucidum polysaccharides have protective effects against apoptosis in neurons
exposed to ischemia/reperfusion injury, but the mechanisms are unclear. The goal of this …

Studies on the neuroprotection of osthole on glutamate-induced apoptotic cells and an Alzheimer's disease mouse model via modulation oxidative stress

Q Chu, Y Zhu, T Cao, Y Zhang, Z Chang, Y Liu… - Applied biochemistry …, 2020 - Springer
In the present study, the neuroprotection of osthole (OST) was confirmed. In l-glutamic acid (l-
Glu)-damaged HT22 cells, a 3-h pre-incubation with OST-enhanced cell viability suppressed …

Chitosan oligosaccharides protect rat primary hippocampal neurons from oligomeric β-amyloid 1-42-induced neurotoxicity

X Dai, P Chang, Q Zhu, W Liu, Y Sun, S Zhu… - Neuroscience Letters, 2013 - Elsevier
Abstract β-Amyloid peptide (Aβ), the major component of senile plaques in patients with
Alzheimer's disease (AD), is believed to facilitate the progressive neurodegeneration that …

Inonotus obliquus polysaccharides protect against Alzheimer's disease by regulating Nrf2 signaling and exerting antioxidative and antiapoptotic effects

Y Han, S Nan, J Fan, Q Chen, Y Zhang - International journal of biological …, 2019 - Elsevier
Inonotus obliquus polysaccharide (IOPS) was initially separated and purified via
precipitation from an aqueous extract with 80% alcohol, a DEAE-52 cellulose anion …

Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II

Y Li, Y Yang, Y Zhao, J Zhang, B Liu, S Jiao… - Free Radical Biology and …, 2019 - Elsevier
Cerebral ischemia induces neuronal cell death in different ways and mitochondrial
dysfunction is an important cause. Astragaloside IV (AIV) is a natural saponin abandent in …