Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

Fetal programming encompasses the role of developmental plasticity in response to
environmental and nutritional signals during early life and its potential adverse …

The traditional view that gene and environment interactions control disease susceptibility
can now be expanded to include epigenetic reprogramming as a key determinant of origins …

The ways in which epigenetic modifications fix the effects of early environmental events,
ensuring sustained responses to transient stimuli that result in modified gene expression …

Significant early life events program individuals toward adult health and disease.
Epidemiologic evidence exists for this concept within communities across the globe as well …

Abstract The Developmental Origins of Health and Disease (DOHaD) hypothesis proposes
that several non-communicable diseases have their origins in prenatal life and in early …

Objective On December 8–9, 2014, the Pennington Biomedical Research Center convened
a scientific symposium to review the state‐of‐the‐science and future directions for the study …

Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

Despite recent progress, we are still far from understanding how, when and where
environmental stressors disturb key epigenetic mechanisms. Thus, identifying the original …

Prenatal programming of the epigenome is a critical determinant in offspring outcome and
stands at the interface between environment and genetics. Maternal experiences such as …