Altered microRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder

MP Moreau, SE Bruse, R David-Rus, S Buyske… - Biological …, 2011 - Elsevier
BACKGROUND: MicroRNAs (miRNAs) are potent regulators of gene expression with
proposed roles in brain development and function. We hypothesized that miRNA expression …

In vivo microRNA detection and quantitation in cerebrospinal fluid

JA Gallego, ML Gordon, K Claycomb, M Bhatt… - Journal of Molecular …, 2012 - Springer
Alterations in microRNA (miRNA) expression in postmortem brain tissue or peripheral blood
have been linked to schizophrenia. Cerebrospinal fluid might provide an in vivo biomarker …

Expression of microRNAs and other small RNAs in prefrontal cortex in schizophrenia, bipolar disorder and depressed subjects

NR Smalheiser, G Lugli, H Zhang, H Rizavi, EH Cook… - PloS one, 2014 - journals.plos.org
Because of the role played by miRNAs in post-transcriptional regulation of an array of
genes, their impact in neuropsychiatric disease pathophysiology has increasingly been …

microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder

DO Perkins, CD Jeffries, LF Jarskog, JM Thomson… - Genome biology, 2007 - Springer
Background microRNAs (miRNAs) are small, noncoding RNA molecules that are now
thought to regulate the expression of many mRNAs. They have been implicated in the …

Aberrant microRNA expression in peripheral plasma and mononuclear cells as specific blood-based biomarkers in schizophrenia patients

X Sun, J Lu, L Zhang, H Song, L Zhao, H Fan… - Journal of clinical …, 2015 - Elsevier
Findings from multiple studies on microRNA (miRNA) expression profiling in schizophrenia
patients have produced conflicting results. In order to investigate miRNA as specific …

Identification of miR-22-3p, miR-92a-3p, and miR-137 in peripheral blood as biomarker for schizophrenia

J Ma, S Shang, J Wang, T Zhang, F Nie, X Song… - Psychiatry …, 2018 - Elsevier
MicroRNAs (miRNAs) are a class of endogenous and non-coding single-stranded RNAs
with length of about 22 nucleotides, and many are evolutionarily conserved. Although …

MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders

AH Kim, M Reimers, B Maher, V Williamson… - Schizophrenia …, 2010 - Elsevier
MicroRNAs (miRNAs) are a large family of small non-coding RNAs which negatively control
gene expression at both the mRNA and protein levels. The number of miRNAs identified is …

Aberrant expression of serum miRNAs in schizophrenia

W Shi, J Du, Y Qi, G Liang, T Wang, S Li, S Xie… - Journal of psychiatric …, 2012 - Elsevier
The circulating miRNAs are sufficiently stable and detectable to serve as clinical biomarkers
as recent studies have revealed that the aberrant expression of circulating miRNAs can …

[HTML][HTML] MicroRNA dysregulation in schizophrenia

NJ Beveridge, MJ Cairns - Neurobiology of disease, 2012 - Elsevier
Schizophrenia is a complex neuropsychiatric disorder that involves disturbances in neural
circuitry and synaptic function. The exquisite network architecture and capacity for discreet …

Dysregulation of miRNA 181b in the temporal cortex in schizophrenia

NJ Beveridge, PA Tooney, AP Carroll… - Human molecular …, 2008 - academic.oup.com
Abstract Analysis of global microRNA (miRNA) expression in postmortem cortical grey
matter from the superior temporal gyrus, revealed significant up-regulation of miR-181b …