Chromosome 1p21. 3 microdeletions comprising DPYD and MIR137 are associated with intellectual disability

MH Willemsen, A Vallès, LAMH Kirkels… - Journal of medical …, 2011 - jmg.bmj.com
Background MicroRNAs (miRNAs) are non-coding gene transcripts involved in post-
transcriptional regulation of genes. Recent studies identified miRNAs as important …

MicroRNAs in psychiatric and neurodevelopmental disorders

B Xu, M Karayiorgou, JA Gogos - Brain research, 2010 - Elsevier
Abnormalities in microRNA (miRNA)-mediated gene regulation have been observed in a
variety of human diseases, especially in cancer. Here, we provide an account of newly …

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

KL Stark, B Xu, A Bagchi, WS Lai, H Liu, R Hsu… - Nature …, 2008 - nature.com
Abstract Individuals with 22q11. 2 microdeletions show behavioral and cognitive deficits and
are at high risk of developing schizophrenia. We analyzed an engineered mouse strain …

Germline deletion of the miR-17∼ 92 cluster causes skeletal and growth defects in humans

L de Pontual, E Yao, P Callier, L Faivre, V Drouin… - Nature …, 2011 - nature.com
MicroRNAs (miRNAs) are key regulators of gene expression in animals and plants. Studies
in a variety of model organisms show that miRNAs modulate developmental processes. To …

Loss of the neurodevelopmental disease-associated gene miR-146a impairs neural progenitor differentiation and causes learning and memory deficits

J Fregeac, S Moriceau, A Poli, LS Nguyen, F Oury… - Molecular autism, 2020 - Springer
Background Formation and maintenance of appropriate neural networks require tight
regulation of neural stem cell proliferation, differentiation, and neurogenesis. microRNAs …

Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders

LS Nguyen, J Fregeac, C Bole-Feysot, N Cagnard… - Molecular autism, 2018 - Springer
Background MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene
expression at the post-transcriptional level. miRNAs have emerged as important modulators …

MicroRNAs of the miR379–410 cluster: New players in embryonic neurogenesis and regulators of neuronal function

J Winter - Neurogenesis, 2015 - Taylor & Francis
The imprinted miR379–410 cluster contains 38 microRNAs (miRNAs) that are involved in
diverse neurodevelopmental processes and are important regulators of neuronal function …

miRNA genes and the brain: implications for psychiatric disorders a

DA Forero, K van Der Ven, P Callaerts… - Human …, 2010 - Wiley Online Library
MicroRNAs (miRNAs) are a class of nonprotein coding genes with a growing importance in
regulatory mechanisms of gene expression related to brain function and plasticity …

Bioimaging of the unbalanced expression of microRNA9 and microRNA9* during the neuronal differentiation of P19 cells

MH Ko, S Kim, DW Hwang, HY Ko, YH Kim… - The FEBS …, 2008 - Wiley Online Library
Generally, the 3′‐end of the duplex microRNA (miR) precursor (pre‐miR) is known to be
stable in vivo and serve as a mature form of miR. However, both the 3′‐end (miR9) and 5 …

Alteration of processing induced by a single nucleotide polymorphism in pri-miR-126

R Harnprasopwat, D Ha, T Toyoshima, H Lodish… - Biochemical and …, 2010 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that inhibit expression of specific target
genes at the post-transcriptional level. Sequence variations in miRNA genes, including pri …