The regulation of synapse formation and plasticity in the developing and adult brain
underlies a complex interplay of intrinsic genetic programs and extrinsic factors. Recent …

MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …

MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-
transcriptional regulators of gene expression. In neurons, the functions of individual miRNAs …

MicroRNAs (miRNAs) are rapidly emerging as central regulators of gene expression in the
postnatal mammalian brain. Initial studies mostly focused on the function of specific miRNAs …

MicroRNAs are non-coding short (~ 23 nucleotides) RNAs that mediate post-transcriptional
regulation through sequence-specific gene silencing. The role of miRNAs in neuronal …

The development and function of the nervous system is orchestrated by a plethora of gene
regulatory mechanisms. MicroRNAs (miRNAs), an abundant class of small non-coding …

Since the discovery of the first microRNA 25 years ago, microRNAs (miRNAs) have emerged
as critical regulators of gene expression within the mammalian brain. miRNAs are small non …

• Introduction• miRNA biogenesis and mode of action• Regulation of miRNA expression•
miRNAs as regulators in the developing nervous system• Synapse development and …

Highlights•miRNAs and RISC are located near synapses.•miRNAs regulate local protein
synthesis in dendrites and axons.•miRNAs play important roles in synapse development and …

MicroRNAs (miRNAs) are endogenous, small non-coding RNA molecules that mediate post-
transcriptional gene suppression by incomplete matches with their host mRNAs. In the …