Segregation of sperm subpopulations in normozoospermic infertile men

J Thilagavathi, S Venkatesh, R Kumar… - Systems Biology in …, 2012 - Taylor & Francis
Sperm function is essential for fertilization and embryogenesis yet semen contain a
heterogeneous population of sperm. This study was designed to evaluate two different …

Total anti‐oxidant status: a biochemical predictor of human male fertility

AL Adeel, S Jahan, F Subhan, W Alam, R Bibi - Andrologia, 2012 - Wiley Online Library
The objective of the study was to assess whether seminal plasma total antioxidant status
(TAS) can be used as a biochemical predictor of male fertility and its variation in different …

More than a simple lock and key mechanism: unraveling the intricacies of sperm-zona pellucida binding

KA Redgrove, RJ Aitken, B Nixon - Binding Protein. Rijeka …, 2012 - books.google.com
Mammalian fertilization involves a concerted interplay between the male and female
gametes that ultimately results in the creation of new life. However, despite the fundamental …

Direct methods for the detection of reactive oxygen species in human semen samples

RJ Aitken, GN De Iuliis, MA Baker - Studies on Men's Health and Fertility, 2012 - Springer
The accurate, selective measurement of reactive oxygen species (ROS) production by
human spermatozoa is still a work-in-progress. Traditionally, chemiluminescence …

ROS and semen quality

R Henkel - Studies on Men's Health and Fertility, 2012 - Springer
Infertility affects an estimate of 50–80× 10 6 (= 7–15% of men at reproductive age) men
globally and annually. Among these men, a large number of patients (25–40%) suffer from …

Oxidative stress, DNA damage, and apoptosis in male infertility

TM Said, C Fischer-Hammadeh, M Hamad… - Studies on men's health …, 2012 - Springer
Oxidative stress, sperm DNA damage, and apoptosis are associated with male infertility as a
cause and as a manifestation. Several clinical conditions and laboratory findings may be …

Oxidative stress and the use of antioxidants for idiopathic OATs

A Agarwal, AH Kashou, LH Sekhon - Studies on Men's Health and Fertility, 2012 - Springer
Aim: To examine the effects of ROS and OS on male fertility and to evaluate the use of
antioxidants as a means of treatment to improve fertilization rates in subfertile males …

Varicocele in adolescence: where are we now?

LS Merriman, AJ Kirsch - Current urology reports, 2012 - Springer
The exact pathophysiology of varicocele and the subsequent alteration of spermatogenesis
has been the subject of much debate. Despite an enormous amount of literature on the …

Role of Protamine Disulphide Cross-Linking in Counteracting Oxidative Damage to DNA

JG Alvarez, J Gosalvez - Studies on Men's Health and Fertility, 2012 - Springer
Free radical (oxygen and nitrogen-derived)-induced sperm DNA damage may take place
during the process of spermatogenesis, during sperm transit through the epididymis, in the …

Loss of intracellular antioxidant enzyme activity during sperm cryopreservation: effects on sperm function after thawing

JG Alvarez - … : Contemporary Clinical Approaches, Andrology, ART & …, 2012 - Springer
Despite advances in cryopreservation methodology, one of the main detrimental effects of
cryopreservation on human spermatozoa is a marked reduction in motility. The primary …