Knight JC (University of Oxford, Oxford, UK). Resolving the variable genome and epigenome
in human disease (Review). J Intern Med 2012; 271: 379–391. The individual human …

To the Editor: Increased expression of the glycoprotein Chitinase-3-like-1 (CHI3L1) gene
has been associated with cancers, autoimmune diseases, and chronic inflammatory …

We have previously shown that rheumatoid arthritis (RA) risk alleles overlap between
different ethnic groups. Here, we utilize a multiethnic approach to show that we can …

Wereldwijd zijn meer dan een half miljard mensen te dik. Dit is een enorm probleem, omdat
zwaarlijvigheid vaak leidt tot ernstige ziekten zoals ouderdomssuikerziekte en Niet …

Asthma and allergic diseases are rapidly becoming the most common chronic diseases in
the developed world. Nearly 1 in 3 Canadians suffer from some form of allergy and more …

Asthma is defined as a chronic inflammatory disorder of the lower airways resulting in an
obstruction of airflow, which may be completely or partially reversed with or without specific …

It is known that genetic variants can affect gene expression, but it is not yet completely clear
through what mechanisms genetic variation mediate this expression. We therefore …

Genetic variation is an important determinant of lung function and risk of chronic obstructive
pulmonary disease (COPD). Genome-wide association studies (GWAS), first described a …