Nuclear factor-κB (NF-κB) is one of the main regulators of inflammatory and immune
responses. It is a family of transcription factors composed of five members: RelA, RelB, cRel …

Nuclear factor kappa B (NF-κB) and p38 mitogen-activated protein kinase (p38 MAPK) are
intimately related to skeletal muscle abnormalities. Since that, an interest has been found to …

Interferons (IFNs) are the most potent mediators of antiviral activities in the immune system.
Viral molecular patterns are detected by receptors of the innate immune system, resulting in …

Der lymphozytenspezifische Transkriptionscoaktivator BOB. 1 bindet zusammen mit den
Transkriptionsfaktoren Oct-1/2 an die DNA und reguliert die spezifische Genexpression in B …

Zwar zeigt die reine NF-κB Bindungsaktivität im Vergleich der Mediane der beiden Gruppen
unterschiedliche Verläufe, eine so hohe Aktivität wie sie bei den BAA-Patienten vorhanden …

Pellino1 was identified as an IRAK binding partner and is involved in Lysine-63
polyubiquitination of IRAK 1/4 and RIP1, which are key mediators of the TLR and IL-1R …

Für Weichgewebssarkome fehlt nach wie vor eine effektive Behandlung über die Resektion
hinaus. Wir untersuchten die Effekte von TRAIL und Taurolidin (TRD) auf humane …

Innate immunity is the primary defense mechanism that recognizes and respond to invading
infectious microbes or their components, known as pathogen-associated molecular patterns …

Nuclear factor-kappa B (NF-κB) was first described as a transcription factor in B cells that
binds to the enhancer element controlling immunoglobulin kappa light chain expression …

Atherosclerosis is one of the most common cardiovascular diseases in Western Countries.
An important feature of the disease is the initiation of atherosclerotic lesions including …