Reestablishment of the inactive X chromosome to the ground state through cell fusion-induced reprogramming

HW Choi, JS Kim, HJ Jang, S Choi, JH Kim… - Cellular and Molecular …, 2012 - Springer
The restricted gene expression pattern of a differentiated cell can be reversed by fusion of
the somatic cell with a more developmentally potent cell type, such as an embryonic stem …

Tracing the genesis of human embryonic stem cells

A Pribluda, JH Hanna - Nature biotechnology, 2012 - nature.com
Tracing the genesis of human embryonic stem cells | Nature Biotechnology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Nuclear reprogramming and the current challenges in advancing personalized pluripotent stem cell-based therapies

JA BYRNE - Gene Therapy and Regulation, 2012 - World Scientific
John Gurdon's discovery that somatic cells could be reprogrammed back into a pluripotent
state has immense implications across multiple different fields, including the future potential …

Эпигенетика плюрипотентных клеток

СП Медведев, ЕА Покушалов… - Acta Naturae …, 2012 - cyberleninka.ru
Плюрипотентность клеток поддерживается сложнейшей системой, включающей
генетический и эпигенетический уровни. Исследования последних лет показывают, что …

Embryonic stem cells: A signalling perspective

MP Stavridis - Mitochondrial DNA, Mitochondria, Disease and Stem …, 2012 - Springer
Since their discovery more than 30 years ago, embryonic stem (ES) cells have been
propelled from relative obscurity into the centre stage of international attention. They have …

[PDF][PDF] Human pluripotent stem cells: glycomic approaches for culturing and characterization

M Mikkola - 2012 - helda.helsinki.fi
Human pluripotent stem cells : glycomic approaches for culturing and characterization Page
1 Helsinki University Biomedical Dissertation No.179 Human pluripotent stem cells: glycomic …

Delineating nuclear reprogramming

J Ooi, P Liu - Protein & cell, 2012 - academic.oup.com
Nuclear reprogramming is described as a molecular switch, triggered by the conversion of
one cell type to another. Several key experiments in the past century have provided insight …

Role of XIST RNA and its interacting protein partners in gene silencing

J Minks - 2012 - open.library.ubc.ca
X-chromosome inactivation ensures equal expression of mammalian male and female X-
linked genes by transcriptionally silencing one X chromosome in each female cell. The …

Reprogramming: a new era in regenerative medicine

VM Heine, S Dooves, D Holmes, J Wagner… - … Pluripotent Stem Cells …, 2012 - Springer
Embryonic stem cells (ESCs) exhibit the capacity for unlimited self-renewal and an ability to
generate all somatic cell lines. However, political, ethical and practical obstacles, such as …

Pluripotent Stem Cells of the Mammalian Early Embryo

MP De Miguel, J Schoorlemmer… - Human Fetal Tissue …, 2012 - Springer
The early embryo harbors the most amazing cells, the embryonic stem (ES) cells, pluripotent
cells capable of generating all the tissues and cell types of a mature animal. Discovery and …