Tracking the progression of the human inner cell mass during embryonic stem cell derivation
T O'leary, B Heindryckx, S Lierman… - Nature …, 2012 - nature.com
The different pluripotent states of mouse embryonic stem cells (ESCs) in vitro have been
shown to correspond to stages of mouse embryonic development,,,,,. For human cells, little …
shown to correspond to stages of mouse embryonic development,,,,,. For human cells, little …
Human embryonic stem cells: prospects for development
MF Pera, AO Trounson - 2004 - journals.biologists.com
It is widely anticipated that human embryonic stem (ES) cells will serve as an experimental
model for studying early development in our species, and, conversely, that studies of …
model for studying early development in our species, and, conversely, that studies of …
Embryonic stem cell identity grounded in the embryo
B Plusa, AK Hadjantonakis - Nature cell biology, 2014 - nature.com
Pluripotent embryonic stem cells (ESCs) can be derived from blastocyst-stage mouse
embryos. However, the exact in vivo counterpart of ESCs has remained elusive. A …
embryos. However, the exact in vivo counterpart of ESCs has remained elusive. A …
Pluripotent states of human embryonic stem cells
Y Chen, D Lai - … Reprogramming (Formerly" Cloning and Stem Cells …, 2015 - liebertpub.com
Since human embryonic stem cells (hESCs) were first isolated and successfully cultured in
vitro, the pluripotent potential of hESCs has been underestimated. The pluripotency of …
vitro, the pluripotent potential of hESCs has been underestimated. The pluripotency of …
Uncovering the true identity of naive pluripotent stem cells
M Welling, N Geijsen - Trends in cell biology, 2013 - cell.com
Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass
(ICM) of blastocyst embryos. Although first characterized over 30 years ago, the ontology of …
(ICM) of blastocyst embryos. Although first characterized over 30 years ago, the ontology of …
Molecular and biological properties of pluripotent embryonic stem cells
S Ohtsuka, S Dalton - Gene therapy, 2008 - nature.com
The inner cell mass of pre-implantation blastocyst stage embryos is a source of cells that can
be cultured indefinitely in vitro as a self-renewing, pluripotent population. In this review, we …
be cultured indefinitely in vitro as a self-renewing, pluripotent population. In this review, we …
The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification
The precise relationship of embryonic stem cells (ESCs) to cells in the mouse embryo
remains controversial. We present transcriptional and functional data to identify the …
remains controversial. We present transcriptional and functional data to identify the …
Metastable pluripotent states in NOD-mouse-derived ESCs
Embryonic stem cells (ESCs) are isolated from the inner cell mass (ICM) of blastocysts,
whereas epiblast stem cells (EpiSCs) are derived from the postimplantation epiblast and …
whereas epiblast stem cells (EpiSCs) are derived from the postimplantation epiblast and …
Transition of inner cell mass to embryonic stem cells: mechanisms, facts, and hypotheses
Embryonic stem cells (ESCs) are immortal stem cells that own multi-lineage differentiation
potential. ESCs are commonly derived from the inner cell mass (ICM) of pre-implantation …
potential. ESCs are commonly derived from the inner cell mass (ICM) of pre-implantation …
Discovering pluripotency: 30 years of mouse embryonic stem cells
M Evans - Nature reviews Molecular cell biology, 2011 - nature.com
Embryonic stem (ES) cells are pluripotent cells isolated from an early embryo and grown as
a cell line in tissue culture. Their discovery came from the conjunction of studies in human …
a cell line in tissue culture. Their discovery came from the conjunction of studies in human …