Purpose: IGFBP7 belongs to a family of insulin-like growth factor-1 regulatory binding
proteins. IGFBP7 hypermethylation is associated with its down-regulation in various …

Promoter hypermethylation is central in deregulating gene expression in cancer.
Identification of novel methylation targets in specific cancers provides a basis for their use as …

Insulin‐like growth factor binding protein‐3 (IGFBP‐3) is postulated to be a mediator of
growth suppression signals. Here, we examined the methylation status of IGFBP‐3 to …

BACKGROUND: The insulin-like growth factor binding protein5 (IGFBP5) is often
dysregulated in human cancers and considered neither a tumor suppressor nor an …

Insulin-like growth factor binding protein-3 (IGFBP-3) is a member of the IGFBP family, which
regulates the mitogenic and antiapoptotic effects of insulin-like growth factors …

Insulin-like growth factor binding protein 7 (IGFBP7) was considered a tumor suppressor
gene in lung cancer. However, the mechanism responsible for the downregulation of this …

Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1), a member of the
IGFBP super family, is down-regulated at the mRNA level in several solid cancers. We …

Purpose Insulin-like growth factor binding protein 7 (IGFBP-7) is considered a tumor
suppressor in various cancers, but its role in colorectal cancer (CRC) is still uncertain. The …

Altered expression of insulin‐like growth factor binding protein 7 (IGFBP7) has been found
in colon cancer, but the exact regulatory mechanism has not been fully investigated. In order …

Insulin-like growth factor binding protein-3 (IGFBP-3) is a pro-apoptotic, anti-metastasic, and
anti-angiogenic protein. Low serum IGFBP-3 has been associated with risk of more …