[HTML][HTML] Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes
Although human induced pluripotent stem cells (hiPSCs) have enormous potential in
regenerative medicine, their epigenetic variability suggests that some lines may not be …
regenerative medicine, their epigenetic variability suggests that some lines may not be …
[HTML][HTML] Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells
KH Narsinh, N Sun, V Sanchez-Freire… - The Journal of …, 2011 - Am Soc Clin Investig
Human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs)
are promising candidate cell sources for regenerative medicine. However, despite the …
are promising candidate cell sources for regenerative medicine. However, despite the …
[HTML][HTML] Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells
S Yokobayashi, Y Yabuta, M Nakagawa, K Okita… - Cell reports, 2021 - cell.com
Human induced pluripotent stem cells (hiPSCs) show variable differentiation potential due to
their epigenomic heterogeneity, whose extent/attributes remain unclear, except for well …
their epigenomic heterogeneity, whose extent/attributes remain unclear, except for well …
Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
Generation of human induced pluripotent stem cells (hiPSCs) by the expression of specific
transcription factors depends on successful epigenetic reprogramming to a pluripotent state …
transcription factors depends on successful epigenetic reprogramming to a pluripotent state …
Concise review: genomic stability of human induced pluripotent stem cells
K Martins‐Taylor, RH Xu - Stem cells, 2012 - academic.oup.com
The usefulness of human induced pluripotent stem cells (hiPSCs) in research and
therapeutic applications highly relies on their genomic integrity and stability. Many …
therapeutic applications highly relies on their genomic integrity and stability. Many …
Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods
Many reprogramming methods can generate human induced pluripotent stem cells (hiPSCs)
that closely resemble human embryonic stem cells (hESCs). This has led to assessments of …
that closely resemble human embryonic stem cells (hESCs). This has led to assessments of …
[HTML][HTML] StemCellDB: the human pluripotent stem cell database at the National Institutes of Health
BS Mallon, JG Chenoweth, KR Johnson, RS Hamilton… - Stem cell …, 2013 - Elsevier
Much of the excitement generated by induced pluripotent stem cell technology is concerned
with the possibility of disease modeling as well as the potential for personalized cell therapy …
with the possibility of disease modeling as well as the potential for personalized cell therapy …
[HTML][HTML] Lab-specific gene expression signatures in pluripotent stem cells
Pluripotent stem cells derived from both embryonic and reprogrammed somatic cells have
significant potential for human regenerative medicine. Despite similarities in developmental …
significant potential for human regenerative medicine. Despite similarities in developmental …
[HTML][HTML] A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals
C Schaniel, P Dhanan, B Hu, Y Xiong, T Raghunandan… - Stem cell reports, 2021 - cell.com
A library of well-characterized human induced pluripotent stem cell (hiPSC) lines from
clinically healthy human subjects could serve as a useful resource of normal controls for in …
clinically healthy human subjects could serve as a useful resource of normal controls for in …
[HTML][HTML] Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
The developmental potential of human pluripotent stem cells suggests that they can produce
disease-relevant cell types for biomedical research. However, substantial variation has been …
disease-relevant cell types for biomedical research. However, substantial variation has been …