[HTML][HTML] Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes

MC Anguera, R Sadreyev, Z Zhang, A Szanto, B Payer… - Cell stem cell, 2012 - cell.com
Although human induced pluripotent stem cells (hiPSCs) have enormous potential in
regenerative medicine, their epigenetic variability suggests that some lines may not be …

[HTML][HTML] Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells

KH Narsinh, N Sun, V Sanchez-Freire… - The Journal of …, 2011 - Am Soc Clin Investig
Human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs)
are promising candidate cell sources for regenerative medicine. However, despite the …

[HTML][HTML] Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells

S Yokobayashi, Y Yabuta, M Nakagawa, K Okita… - Cell reports, 2021 - cell.com
Human induced pluripotent stem cells (hiPSCs) show variable differentiation potential due to
their epigenomic heterogeneity, whose extent/attributes remain unclear, except for well …

Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells

S Ruiz, D Diep, A Gore… - Proceedings of the …, 2012 - National Acad Sciences
Generation of human induced pluripotent stem cells (hiPSCs) by the expression of specific
transcription factors depends on successful epigenetic reprogramming to a pluripotent state …

Concise review: genomic stability of human induced pluripotent stem cells

K Martins‐Taylor, RH Xu - Stem cells, 2012 - academic.oup.com
The usefulness of human induced pluripotent stem cells (hiPSCs) in research and
therapeutic applications highly relies on their genomic integrity and stability. Many …

Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods

JM Churko, J Lee, M Ameen, M Gu… - Nature biomedical …, 2017 - nature.com
Many reprogramming methods can generate human induced pluripotent stem cells (hiPSCs)
that closely resemble human embryonic stem cells (hESCs). This has led to assessments of …

[HTML][HTML] StemCellDB: the human pluripotent stem cell database at the National Institutes of Health

BS Mallon, JG Chenoweth, KR Johnson, RS Hamilton… - Stem cell …, 2013 - Elsevier
Much of the excitement generated by induced pluripotent stem cell technology is concerned
with the possibility of disease modeling as well as the potential for personalized cell therapy …

[HTML][HTML] Lab-specific gene expression signatures in pluripotent stem cells

AM Newman, JB Cooper - Cell stem cell, 2010 - cell.com
Pluripotent stem cells derived from both embryonic and reprogrammed somatic cells have
significant potential for human regenerative medicine. Despite similarities in developmental …

[HTML][HTML] A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals

C Schaniel, P Dhanan, B Hu, Y Xiong, T Raghunandan… - Stem cell reports, 2021 - cell.com
A library of well-characterized human induced pluripotent stem cell (hiPSC) lines from
clinically healthy human subjects could serve as a useful resource of normal controls for in …

[HTML][HTML] Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

C Bock, E Kiskinis, G Verstappen, H Gu, G Boulting… - Cell, 2011 - cell.com
The developmental potential of human pluripotent stem cells suggests that they can produce
disease-relevant cell types for biomedical research. However, substantial variation has been …