The noncanonical NF‐κB pathway
SC Sun - Immunological reviews, 2012 - Wiley Online Library
The noncanonical nuclear factor‐κB (NF‐κB) signaling pathway mediates activation of the
p52/RelB NF‐κB complex and, thereby, regulates specific immunological processes. This …
p52/RelB NF‐κB complex and, thereby, regulates specific immunological processes. This …
[HTML][HTML] Non-canonical NF-κB signaling pathway
SC Sun - Cell research, 2011 - nature.com
The non-canonical NF-κB pathway is an important arm of NF-κB signaling that
predominantly targets activation of the p52/RelB NF-κB complex. This pathway depends on …
predominantly targets activation of the p52/RelB NF-κB complex. This pathway depends on …
New insights into NF-κB regulation and function
NF-κB (nuclear factor-κB) transcription factors have multiple critical roles in the regulation of
immune responses. In unstimulated cells, NF-κB proteins are sequestered in the cytoplasm …
immune responses. In unstimulated cells, NF-κB proteins are sequestered in the cytoplasm …
Control of canonical NF-κB activation through the NIK–IKK complex pathway
B Zarnegar, S Yamazaki, JQ He… - Proceedings of the …, 2008 - National Acad Sciences
Articles in recent years have described two separate and distinct NF-κB activation pathways
that result in the differential activation of p50-or p52-containing NF-κB complexes. Studies …
that result in the differential activation of p50-or p52-containing NF-κB complexes. Studies …
Non‐canonical NF‐κB signaling activation and regulation: principles and perspectives
Nuclear‐factor κB (NF‐κB) transcription factors are activated by a wide variety of stimuli in
diverse cell types and control key aspects of immune function and development. Receptor …
diverse cell types and control key aspects of immune function and development. Receptor …
[HTML][HTML] Receptor-specific signaling for both the alternative and the canonical NF-κB activation pathways by NF-κB-inducing kinase
The NF-κB-inducing kinase (NIK) induces proteolytic processing of NF-κB2/p100 and,
hence, the generation of NF-κB dimers such as p52: RelB but was suggested not to signal …
hence, the generation of NF-κB dimers such as p52: RelB but was suggested not to signal …
Phosphorylation meets ubiquitination: the control of NF-κB activity
M Karin, Y Ben-Neriah - Annual review of immunology, 2000 - annualreviews.org
NF-κB (nuclear factor-κB) is a collective name for inducible dimeric transcription factors
composed of members of the Rel family of DNA-binding proteins that recognize a common …
composed of members of the Rel family of DNA-binding proteins that recognize a common …
[HTML][HTML] Regulation of the NF-κB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
The NF-κB family of transcription factors plays a pivotal role in regulation of diverse
biological processes, including immune responses, cell growth, and apoptosis. Activation of …
biological processes, including immune responses, cell growth, and apoptosis. Activation of …
The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development
E Dejardin - Biochemical pharmacology, 2006 - Elsevier
The past two decades have led to a tremendous work on the transcription factor NF-κB and
its molecular mechanisms of activation. The nuclear translocation of NF-κB is controlled by …
its molecular mechanisms of activation. The nuclear translocation of NF-κB is controlled by …