Development and validation of an HPLC-DAD method for quantification of bornesitol in extracts from Hancornia speciosa leaves after derivatization with p …

ABD Pereira, TM Veríssimo, MA de Oliveira… - … of Chromatography B, 2012 - Elsevier
Cylitol l-(+)-bornesitol is regarded as a bioactive constituent from Hancornia speciosa
leaves, a plant species traditionally used in Brazil to treat diabetes and hypertension. We …

Forced degradation of L-(+)-bornesitol, a bioactive marker of Hancornia speciosa: Development and validation of stability indicating UHPLC-MS method and effect of …

JH de Sousa Gomes, GC da Silva, SF Côrtes… - … of Chromatography B, 2018 - Elsevier
The antihypertensive activity of the medicinal plant Hancornia speciosa has been previously
demonstrated by us, being the activity ascribed to polyphenols and cyclitols like l-(+) …

[HTML][HTML] Determination of L-(+)-bornesitol, the hypotensive constituent of Hancornia speciosa, in rat plasma by LC-MS/MS and its application on a pharmacokinetic …

LN Moreira, C Feltrin, JE Goncalves… - Biomedicine & …, 2020 - Elsevier
Hancornia speciosa is a medicinal plant with proven antihypertensive activity. The cyclitol l-
(+)-bornesitol is the main constituent of its leaves and is a potent inhibitor of the angiotensin …

The Cyclitol L-(+)-bornesitol as an active marker for the cardiovascular activity of the brazilian medicinal plant Hancornia speciosa

LN Moreira, GC Silva, DV Câmara… - Biological and …, 2019 - jstage.jst.go.jp
The cyclitol bornesitol is the main constituent of the leaves from the antihypertensive
medicinal plant Hancornia speciosa. This study aimed to investigate the ability of bornesitol …

[HTML][HTML] Hancornia speciosa Gomes induces hypotensive effect through inhibition of ACE and increase on NO

GC Silva, FC Braga, MP Lima, JL Pesquero… - Journal of …, 2011 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Hancornia speciosa Gomes are
popularly used in Brazil to treat diabetes and hypertension. Cardiovascular diseases are the …

Definition of chemical markers for Hancornia speciosa Gomes by chemometric analysis based on the chemical composition of extracts, their vasorelaxant effect and α …

ABD Pereira, JH de Sousa Gomes, AC Pereira… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Hancornia speciosa Gomes (Apocynaceae) is a
tree found in the Brazilian savannah, traditionally used to treat several diseases, including …

[HTML][HTML] Hancornia speciosa Gomes (Apocynaceae) as a potential anti-diabetic drug

AC Pereira, ABD Pereira, CCL Moreira… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance The leaves of Hancornia speciosa Gomes are traditionally
used to treat diabetes in Brazil. The aim of the study is to evaluate the potential anti-diabetic …

[HTML][HTML] Potent antihypertensive effect of Hancornia speciosa leaves extract

GC Silva, FC Braga, VS Lemos, SF Cortes - Phytomedicine, 2016 - Elsevier
Abstract Background Hancornia speciosa Gomes is an herb traditionally used in Brazil for
blood pressure control. Purpose The present work investigated the antihypertensive effect of …

Structural characterization of a proanthocyanidin-rich fraction from Hancornia speciosa leaves and its effect on the release of pro-inflammatory cytokines and oxidative …

WOC Junior, MLR Guimarães, KM Freitas… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance In Brazil, the leaves of Hancornia speciosa
Gomes have a traditional use for treating hypertension and diabetes. Experimental …

Rapid determination of bioactive compounds in the different organs of Salvia Miltiorrhiza by UPLC-MS/MS

HY Lin, TS Lin, CS Wang, HJ Chien, YM Juang… - … of Chromatography B, 2019 - Elsevier
Salvia miltiorrhiza has been widely used in Asia for medicinal purposes for> 1000 years due
to the high levels of bioactive constituents it contains. In this study, a simple and rapid …