[HTML][HTML] REST–mediated recruitment of Polycomb repressor complexes in mammalian cells
N Dietrich, M Lerdrup, E Landt, S Agrawal-Singh… - PLoS …, 2012 - journals.plos.org
Polycomb Repressive Complex (PRC) 1 and PRC2 regulate genes involved in
differentiation and development. However, the mechanism for how PRC1 and PRC2 are …
differentiation and development. However, the mechanism for how PRC1 and PRC2 are …
REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements
X Ren, TK Kerppola - Molecular and cellular biology, 2011 - Taylor & Francis
Polycomb group (PcG) proteins control the epigenetic inheritance of transcription regulatory
states during development. Progression from pluripotency to differentiation requires the …
states during development. Progression from pluripotency to differentiation requires the …
[HTML][HTML] An evolutionary conserved epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS
Polycomb response elements (PREs) are specific DNA sequences that stably maintain the
developmental pattern of gene expression. Drosophila PREs are well characterized …
developmental pattern of gene expression. Drosophila PREs are well characterized …
[HTML][HTML] Ubiquitination-independent repression of PRC1 targets during neuronal fate restriction in the developing mouse neocortex
Polycomb repressive complex (PRC) 1 maintains developmental genes in a poised state
through monoubiquitination (Ub) of histone H2A. Although Ub-independent functions of …
through monoubiquitination (Ub) of histone H2A. Although Ub-independent functions of …
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity
The Polycomb group (PcG) proteins mediate heritable silencing of developmental regulators
in metazoans, participating in one of two distinct multimeric protein complexes, the …
in metazoans, participating in one of two distinct multimeric protein complexes, the …
Polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells
HF Jørgensen, S Giadrossi, M Casanova, M Endoh… - Cell Cycle, 2006 - Taylor & Francis
Stem cells are characterised by a capacity to self renew and generate progenycapable of
differentiating along several defined lineage paths. Embryonic Stem (ES) cellsare derived …
differentiating along several defined lineage paths. Embryonic Stem (ES) cellsare derived …
[HTML][HTML] MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1. 6
B Stielow, F Finkernagel, T Stiewe, A Nist… - PLoS genetics, 2018 - journals.plos.org
Diverse Polycomb repressive complexes 1 (PRC1) play essential roles in gene regulation,
differentiation and development. Six major groups of PRC1 complexes that differ in their …
differentiation and development. Six major groups of PRC1 complexes that differ in their …
PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency
The Polycomb repressive system plays a fundamental role in controlling gene expression
during mammalian development. To achieve this, Polycomb repressive complexes 1 and 2 …
during mammalian development. To achieve this, Polycomb repressive complexes 1 and 2 …
Targeting Polycomb systems to regulate gene expression: modifications to a complex story
Polycomb group proteins are transcriptional repressors that are essential for normal gene
regulation during development. Recent studies suggest that Polycomb repressive …
regulation during development. Recent studies suggest that Polycomb repressive …
[HTML][HTML] PRC2. 1-and PRC2. 2-specific accessory proteins drive recruitment of different forms of canonical PRC1
Summary Polycomb repressive complex 2 (PRC2) mediates H3K27me3 deposition, which is
thought to recruit canonical PRC1 (cPRC1) via chromodomain-containing CBX proteins to …
thought to recruit canonical PRC1 (cPRC1) via chromodomain-containing CBX proteins to …