Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamsters

Z Qiang, SO Lee, Z Ye, X Wu… - Phytotherapy …, 2012 - Wiley Online Library
A study was conducted in hamsters to determine if artichoke leaf extract (ALE) could lower
plasma total and non‐HDL cholesterol by increasing fecal excretion of neutral bile acids and …

Choleretic activity and biliary elimination of lipids and bile acids induced by an artichoke leaf extract in rats

TS Rodriguez, DG Giménez, R De la Puerta Vázquez - Phytomedicine, 2002 - Elsevier
The therapeutic properties of artichoke (Cynara scolymus L.) preparations have been known
since ancient times. The traditional use of artichoke leaf extract (ALE) in gastroenterology is …

Inhibition of cholesterol biosynthesis in primary cultured rat hepatocytes by artichoke (Cynara scolymus L.) extracts

R Gebhardt - Journal of Pharmacology and Experimental …, 1998 - ASPET
High-dose aqueous extracts from artichoke leaves were found to inhibit cholesterol
biosynthesis from 14C-acetate in primary cultured rat hepatocytes in a concentration …

Artichoke leaf extract for serum cholesterol reduction.

MH Pittler, E Ernst - 1998 - cabidigitallibrary.org
Elevated serum cholesterol is a universally accepted, major risk factor for coronary heart
disease. Beneficial effects of artichoke (Cynara scolymus) extract for serum cholesterol …

Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled …

R Bundy, AF Walker, RW Middleton, C Wallis… - Phytomedicine, 2008 - Elsevier
Cardiovascular diseases are the chief causes of death in the UK, and are associated with
high circulating levels of total cholesterol in the plasma. Artichoke leaf extracts (ALEs) have …

Effects of artichoke leaf extract (ALE) on lipoprotein metabolism in vitro and in vivo

O Petrowicz, R Gebhardt, M Donner, P Schwandt… - Atherosclerosis, 1997 - infona.pl
Several clinical data indicate a cholesterol lowering potency of ALE. We have shown that
ALE significantly reduces the de-novo cholesterol biosynthesis in primary cultured rat and …

Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind …

M Rondanelli, A Giacosa, A Opizzi… - … Journal of Food …, 2013 - Taylor & Francis
The aim of this study was to evaluate the effects of artichoke leaf extract (ALE)
supplementation (250 mg, 2 bid) on the lipid pattern. A randomized, double-blind, placebo …

Inhibition of cholesterol biosynthesis in HepG2 cells by artichoke extracts is reinforced by glucosidase pretreatment

R Gebhardt - Phytotherapy research, 2002 - Wiley Online Library
High‐dose aqueous extracts from artichoke leaves were found to inhibit cholesterol
biosynthesis from 14C‐acetate rather moderately in HepG2 cells in contrast to primary …

Hypolipidaemic activity of α-asarone in mice.

L Garduno, M Salazar, S Salazar, ME Morelos… - 1997 - cabidigitallibrary.org
Abstract α-Asarone was extracted from the bark of Guatteria gaumeri and administered via
gastric intubation (0, 40 or 80 mg/kg daily) to mice fed normal or high cholesterol diets for 6 …

Dietary horseradish reduces plasma cholesterol in mice

B Balasinska, C Nicolle, E Gueux, A Majewska… - Nutrition research, 2005 - Elsevier
Horseradish is a traditional spice consumed in Eastern Europe. It is a major source of
isothiocyanates; however, it contains numerous other compounds. The present study was …